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Computer-Guided Approach to Access the Anti-influenza Activity of Licorice Constituents
[Image: see text] Neuraminidase (NA), a key enzyme in viral replication, is the first-line drug target to combat influenza. On the basis of a shape-focused virtual screening, the roots of Glycyrrhiza glabra (licorice) were identified as plant species with an accumulation of constituents that show 3D...
Autores principales: | Grienke, Ulrike, Braun, Heike, Seidel, Nora, Kirchmair, Johannes, Richter, Martina, Krumbholz, Andi, von Grafenstein, Susanne, Liedl, Klaus R., Schmidtke, Michaela, Rollinger, Judith M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical
Society and American
Society of Pharmacognosy
2013
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971757/ https://www.ncbi.nlm.nih.gov/pubmed/24313801 http://dx.doi.org/10.1021/np400817j |
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