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Asymmetric Palladium-Catalyzed Directed Intermolecular Fluoroarylation of Styrenes
[Image: see text] A mild catalytic asymmetric direct fluoro-arylation of styrenes has been developed. The palladium-catalyzed three-component coupling of Selectfluor, a styrene and a boronic acid, provides chiral monofluorinated compounds in good yield and in high enantiomeric excess. A mechanism pr...
Autores principales: | Talbot, Eric P. A., Fernandes, Talita de A., McKenna, Jeffrey M., Toste, F. Dean |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971964/ https://www.ncbi.nlm.nih.gov/pubmed/24617344 http://dx.doi.org/10.1021/ja412881j |
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