Using Linkage Analysis to Detect Gene-Gene Interaction by Stratifying Family Data on Known Disease, or Disease-Associated, Alleles

Detecting gene-gene interaction in complex diseases is a major challenge for common disease genetics. Most interaction detection approaches use disease-marker associations and such methods have low power and unknown reliability in real data. We developed and tested a powerful linkage-analysis-based...

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Detalles Bibliográficos
Autores principales: Corso, Barbara, Greenberg, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972093/
https://www.ncbi.nlm.nih.gov/pubmed/24690899
http://dx.doi.org/10.1371/journal.pone.0093398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972093/
https://www.ncbi.nlm.nih.gov/pubmed/24690899
http://dx.doi.org/10.1371/journal.pone.0093398

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