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Uncovering the Basis of ATP Hydrolysis Activity in Purified Human p53 Protein: A Reinvestigation
p53 is one of the most well studied tumor suppressor proteins and regarded as the guardian of the genome. The protein mediates cell-cycle arrest, apoptosis in response to myriads of cellular stresses including DNA damage via its trascriptional as well as non-transcriptional roles. ATP binding/hydrol...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972114/ https://www.ncbi.nlm.nih.gov/pubmed/24691158 http://dx.doi.org/10.1371/journal.pone.0093652 |