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Discovery of a Natural Product-Like iNOS Inhibitor by Molecular Docking with Potential Neuroprotective Effects In Vivo

In this study, we applied structure-based virtual screening techniques to identify natural product or natural product-like inhibitors of iNOS. The iNOS inhibitory activity of the hit compounds was characterized using cellular assays and an in vivo zebrafish larvae model. The natural product-like com...

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Detalles Bibliográficos
Autores principales:	Zhong, Hai-Jing, Liu, Li-Juan, Chong, Cheong-Meng, Lu, Lihua, Wang, Modi, Chan, Daniel Shiu-Hin, Chan, Philip Wai Hong, Lee, Simon Ming-Yuen, Ma, Dik-Lung, Leung, Chung-Hang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972188/ https://www.ncbi.nlm.nih.gov/pubmed/24690920 http://dx.doi.org/10.1371/journal.pone.0092905

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