Disulfiram Suppresses Growth of the Malignant Pleural Mesothelioma Cells in Part by Inducing Apoptosis

Dithiocarbamate compound Disulfiram (DSF) that binds with copper and functions as an inhibitor of aldehyde dehydrogenase is a Food and Drug Administration approved agent for treatment of alcoholism. Copper complexed DSF (DSF-Cu) also possesses anti-tumor and chemosensitizing properties; however, its...

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Detalles Bibliográficos
Autores principales: Cheriyan, Vino T., Wang, Ying, Muthu, Magesh, Jamal, Shazia, Chen, Di, Yang, Huanjie, Polin, Lisa A., Tarca, Adi L., Pass, Harvey I., Dou, Q. Ping, Sharma, Sunita, Wali, Anil, Rishi, Arun K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972204/
https://www.ncbi.nlm.nih.gov/pubmed/24690739
http://dx.doi.org/10.1371/journal.pone.0093711

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