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Immunization with a Peptide Containing MHC Class I and II Epitopes Derived from the Tumor Antigen SIM2 Induces an Effective CD4 and CD8 T-Cell Response

Here, we sought to determine whether peptide vaccines designed harbor both class I as well as class II restricted antigenic motifs could concurrently induce CD4 and CD8 T cell activation against autologous tumor antigens. Based on our prior genome-wide interrogation of human prostate cancer tissues...

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Detalles Bibliográficos
Autores principales:	Kissick, Haydn T., Sanda, Martin G., Dunn, Laura K., Arredouani, Mohamed S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972205/ https://www.ncbi.nlm.nih.gov/pubmed/24690990 http://dx.doi.org/10.1371/journal.pone.0093231

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