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Apoptotic Response through a High Mobility Box 1 Protein-Dependent Mechanism in LPS/GalN-Induced Mouse Liver Failure and Glycyrrhizin-Mediated Inhibition

HMGB1 is a nuclear component involved in nucleosome stabilization and transcription regulation, but extracellularly it is able to serve as a potential late mediator of lethality. In the present study, we explored inflammation-promoting activity of HMGB1 and blockade of extracellular release of HMGB1...

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Detalles Bibliográficos
Autores principales:	Kuroda, Noriyuki, Inoue, Kouji, Ikeda, Tadayuki, Hara, Yaiko, Wake, Kenjiro, Sato, Tetsuji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972228/ https://www.ncbi.nlm.nih.gov/pubmed/24690901 http://dx.doi.org/10.1371/journal.pone.0092884

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