The Copper Metabolism MURR1 Domain Protein 1 (COMMD1) Modulates the Aggregation of Misfolded Protein Species in a Client-Specific Manner

The Copper Metabolism MURR1 domain protein 1 (COMMD1) is a protein involved in multiple cellular pathways, including copper homeostasis, NF-κB and hypoxia signalling. Acting as a scaffold protein, COMMD1 mediates the levels, stability and proteolysis of its substrates (e.g. the copper-transporters A...

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Detalles Bibliográficos
Autores principales: Vonk, Willianne I. M., Kakkar, Vaishali, Bartuzi, Paulina, Jaarsma, Dick, Berger, Ruud, Hofker, Marten H., Klomp, Leo W. J., Wijmenga, Cisca, Kampinga, Harm H., van de Sluis, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972230/
https://www.ncbi.nlm.nih.gov/pubmed/24691167
http://dx.doi.org/10.1371/journal.pone.0092408

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