Serum Bilirubin Affects Graft Outcomes through UDP-Glucuronosyltransferase Sequence Variation in Kidney Transplantation

BACKGROUND: Oxidative stress is a major mediator of adverse outcome after kidney transplantation. Bilirubin is produced by heme oxygenase-1 (HO-1), catalyzed by UDP-glucuronosyltransferase (UGT1A1), and has potential as an antioxidant. In this study, we investigated the effects of HO-1 and UGT1A1 se...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Jung Pyo, Kim, Do Hyoung, Yang, Seung Hee, Hwang, Jin Ho, An, Jung Nam, Min, Sang Il, Ha, Jongwon, Oh, Yun Kyu, Kim, Yon Su, Lim, Chun Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972238/
https://www.ncbi.nlm.nih.gov/pubmed/24690955
http://dx.doi.org/10.1371/journal.pone.0093633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972238/
https://www.ncbi.nlm.nih.gov/pubmed/24690955
http://dx.doi.org/10.1371/journal.pone.0093633

Ejemplares similares