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Serum Bilirubin Affects Graft Outcomes through UDP-Glucuronosyltransferase Sequence Variation in Kidney Transplantation
BACKGROUND: Oxidative stress is a major mediator of adverse outcome after kidney transplantation. Bilirubin is produced by heme oxygenase-1 (HO-1), catalyzed by UDP-glucuronosyltransferase (UGT1A1), and has potential as an antioxidant. In this study, we investigated the effects of HO-1 and UGT1A1 se...
Autores principales: | Lee, Jung Pyo, Kim, Do Hyoung, Yang, Seung Hee, Hwang, Jin Ho, An, Jung Nam, Min, Sang Il, Ha, Jongwon, Oh, Yun Kyu, Kim, Yon Su, Lim, Chun Soo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972238/ https://www.ncbi.nlm.nih.gov/pubmed/24690955 http://dx.doi.org/10.1371/journal.pone.0093633 |
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