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Transcription Factor ZBED6 Mediates IGF2 Gene Expression by Regulating Promoter Activity and DNA Methylation in Myoblasts
Zinc finger, BED-type containing 6 (ZBED6) is an important transcription factor in placental mammals, affecting development, cell proliferation and growth. In this study, we found that the expression of the ZBED6 and IGF2 were upregulated during C2C12 differentiation. The IGF2 expression levels were...
Autores principales: | Huang, Yong-Zhen, Zhang, Liang-Zhi, Lai, Xin-Sheng, Li, Ming-Xun, Sun, Yu-Jia, Li, Cong-Jun, Lan, Xian-Yong, Lei, Chu-Zhao, Zhang, Chun-Lei, Zhao, Xin, Chen, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972505/ https://www.ncbi.nlm.nih.gov/pubmed/24691566 http://dx.doi.org/10.1038/srep04570 |
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