Oral cancer cells may rewire alternative metabolic pathways to survive from siRNA silencing of metabolic enzymes

BACKGROUND: Cancer cells may undergo metabolic adaptations that support their growth as well as drug resistance properties. The purpose of this study is to test if oral cancer cells can overcome the metabolic defects introduced by using small interfering RNA (siRNA) to knock down their expression of...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Chai, Yang D, Brumbaugh, Jeffrey, Liu, Xiaojun, Rabii, Ramin, Feng, Sizhe, Misuno, Kaori, Messadi, Diana, Hu, Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972515/
https://www.ncbi.nlm.nih.gov/pubmed/24666435
http://dx.doi.org/10.1186/1471-2407-14-223

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