Cargando…

Genital Infection with Herpes Simplex Virus Types 1 and 2 in Women from Natal, Brazil

Objective. To evaluate the prevalence of HSV-1 and HSV-2 in pregnant and nonpregnant women, testing the correlation between DNA of the viruses with colposcopic and/or cytological changes, and evaluate association with sociodemographic characteristics and sexual activity. Methods. Included in this st...

Descripción completa

Detalles Bibliográficos
Autores principales: Miranda, Cleine Aglacy Nunes, Lima, Érika Galvão, de Lima, Diego Breno Soares, Cobucci, Ricardo Ney Oliveira, Cornetta, Maria da Conceição de Mesquita, Fernandes, Thales Allyrio Araújo de Medeiros, de Azevedo, Paulo Roberto Medeiros, de Azevedo, Jenner Chrystian Veríssimo, de Araújo, Josélio Maria Galvão, Fernandes, José Veríssimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972835/
https://www.ncbi.nlm.nih.gov/pubmed/25006480
http://dx.doi.org/10.1155/2014/323657
_version_ 1782309624069750784
author Miranda, Cleine Aglacy Nunes
Lima, Érika Galvão
de Lima, Diego Breno Soares
Cobucci, Ricardo Ney Oliveira
Cornetta, Maria da Conceição de Mesquita
Fernandes, Thales Allyrio Araújo de Medeiros
de Azevedo, Paulo Roberto Medeiros
de Azevedo, Jenner Chrystian Veríssimo
de Araújo, Josélio Maria Galvão
Fernandes, José Veríssimo
author_facet Miranda, Cleine Aglacy Nunes
Lima, Érika Galvão
de Lima, Diego Breno Soares
Cobucci, Ricardo Ney Oliveira
Cornetta, Maria da Conceição de Mesquita
Fernandes, Thales Allyrio Araújo de Medeiros
de Azevedo, Paulo Roberto Medeiros
de Azevedo, Jenner Chrystian Veríssimo
de Araújo, Josélio Maria Galvão
Fernandes, José Veríssimo
author_sort Miranda, Cleine Aglacy Nunes
collection PubMed
description Objective. To evaluate the prevalence of HSV-1 and HSV-2 in pregnant and nonpregnant women, testing the correlation between DNA of the viruses with colposcopic and/or cytological changes, and evaluate association with sociodemographic characteristics and sexual activity. Methods. Included in this study were 106 pregnant and 130 nonpregnant women treated at primary health care units of Natal, Brazil, in the period 2010-2011. The patients were examined by colposcopy, and two cervical specimens were collected: one for cytology examination and another for analysis by PCR for detection of HSV-1 and HSV-2. Results. HSV-1 alone was detected in 16.0% of pregnant and 30.0% of nonpregnant women. For HSV-2, these rates were 12.3% and 15.5%, respectively. HSV-2 had a higher correlation with cytology and/or colposcopy changes than HSV-1 did. Genital HSV-1 infection was not associated with any of the variables tested, whereas HSV-2 infection was associated with ethnicity, marital status, and number of sexual partners. Conclusions. The prevalence of HSV-1 was higher than that observed for HSV-2 in both pregnant and nonpregnant women. The genital infection by HSV-2 was higher in women with changed colposcopy and/or cytology, and it was associated with ethnicity, marital status, and number of sexual partners.
format Online
Article
Text
id pubmed-3972835
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-39728352014-07-08 Genital Infection with Herpes Simplex Virus Types 1 and 2 in Women from Natal, Brazil Miranda, Cleine Aglacy Nunes Lima, Érika Galvão de Lima, Diego Breno Soares Cobucci, Ricardo Ney Oliveira Cornetta, Maria da Conceição de Mesquita Fernandes, Thales Allyrio Araújo de Medeiros de Azevedo, Paulo Roberto Medeiros de Azevedo, Jenner Chrystian Veríssimo de Araújo, Josélio Maria Galvão Fernandes, José Veríssimo ISRN Obstet Gynecol Research Article Objective. To evaluate the prevalence of HSV-1 and HSV-2 in pregnant and nonpregnant women, testing the correlation between DNA of the viruses with colposcopic and/or cytological changes, and evaluate association with sociodemographic characteristics and sexual activity. Methods. Included in this study were 106 pregnant and 130 nonpregnant women treated at primary health care units of Natal, Brazil, in the period 2010-2011. The patients were examined by colposcopy, and two cervical specimens were collected: one for cytology examination and another for analysis by PCR for detection of HSV-1 and HSV-2. Results. HSV-1 alone was detected in 16.0% of pregnant and 30.0% of nonpregnant women. For HSV-2, these rates were 12.3% and 15.5%, respectively. HSV-2 had a higher correlation with cytology and/or colposcopy changes than HSV-1 did. Genital HSV-1 infection was not associated with any of the variables tested, whereas HSV-2 infection was associated with ethnicity, marital status, and number of sexual partners. Conclusions. The prevalence of HSV-1 was higher than that observed for HSV-2 in both pregnant and nonpregnant women. The genital infection by HSV-2 was higher in women with changed colposcopy and/or cytology, and it was associated with ethnicity, marital status, and number of sexual partners. Hindawi Publishing Corporation 2014-03-11 /pmc/articles/PMC3972835/ /pubmed/25006480 http://dx.doi.org/10.1155/2014/323657 Text en Copyright © 2014 Cleine Aglacy Nunes Miranda et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Miranda, Cleine Aglacy Nunes
Lima, Érika Galvão
de Lima, Diego Breno Soares
Cobucci, Ricardo Ney Oliveira
Cornetta, Maria da Conceição de Mesquita
Fernandes, Thales Allyrio Araújo de Medeiros
de Azevedo, Paulo Roberto Medeiros
de Azevedo, Jenner Chrystian Veríssimo
de Araújo, Josélio Maria Galvão
Fernandes, José Veríssimo
Genital Infection with Herpes Simplex Virus Types 1 and 2 in Women from Natal, Brazil
title Genital Infection with Herpes Simplex Virus Types 1 and 2 in Women from Natal, Brazil
title_full Genital Infection with Herpes Simplex Virus Types 1 and 2 in Women from Natal, Brazil
title_fullStr Genital Infection with Herpes Simplex Virus Types 1 and 2 in Women from Natal, Brazil
title_full_unstemmed Genital Infection with Herpes Simplex Virus Types 1 and 2 in Women from Natal, Brazil
title_short Genital Infection with Herpes Simplex Virus Types 1 and 2 in Women from Natal, Brazil
title_sort genital infection with herpes simplex virus types 1 and 2 in women from natal, brazil
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972835/
https://www.ncbi.nlm.nih.gov/pubmed/25006480
http://dx.doi.org/10.1155/2014/323657
work_keys_str_mv AT mirandacleineaglacynunes genitalinfectionwithherpessimplexvirustypes1and2inwomenfromnatalbrazil
AT limaerikagalvao genitalinfectionwithherpessimplexvirustypes1and2inwomenfromnatalbrazil
AT delimadiegobrenosoares genitalinfectionwithherpessimplexvirustypes1and2inwomenfromnatalbrazil
AT cobucciricardoneyoliveira genitalinfectionwithherpessimplexvirustypes1and2inwomenfromnatalbrazil
AT cornettamariadaconceicaodemesquita genitalinfectionwithherpessimplexvirustypes1and2inwomenfromnatalbrazil
AT fernandesthalesallyrioaraujodemedeiros genitalinfectionwithherpessimplexvirustypes1and2inwomenfromnatalbrazil
AT deazevedopaulorobertomedeiros genitalinfectionwithherpessimplexvirustypes1and2inwomenfromnatalbrazil
AT deazevedojennerchrystianverissimo genitalinfectionwithherpessimplexvirustypes1and2inwomenfromnatalbrazil
AT dearaujojoseliomariagalvao genitalinfectionwithherpessimplexvirustypes1and2inwomenfromnatalbrazil
AT fernandesjoseverissimo genitalinfectionwithherpessimplexvirustypes1and2inwomenfromnatalbrazil