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Genital Infection with Herpes Simplex Virus Types 1 and 2 in Women from Natal, Brazil
Objective. To evaluate the prevalence of HSV-1 and HSV-2 in pregnant and nonpregnant women, testing the correlation between DNA of the viruses with colposcopic and/or cytological changes, and evaluate association with sociodemographic characteristics and sexual activity. Methods. Included in this st...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972835/ https://www.ncbi.nlm.nih.gov/pubmed/25006480 http://dx.doi.org/10.1155/2014/323657 |
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author | Miranda, Cleine Aglacy Nunes Lima, Érika Galvão de Lima, Diego Breno Soares Cobucci, Ricardo Ney Oliveira Cornetta, Maria da Conceição de Mesquita Fernandes, Thales Allyrio Araújo de Medeiros de Azevedo, Paulo Roberto Medeiros de Azevedo, Jenner Chrystian Veríssimo de Araújo, Josélio Maria Galvão Fernandes, José Veríssimo |
author_facet | Miranda, Cleine Aglacy Nunes Lima, Érika Galvão de Lima, Diego Breno Soares Cobucci, Ricardo Ney Oliveira Cornetta, Maria da Conceição de Mesquita Fernandes, Thales Allyrio Araújo de Medeiros de Azevedo, Paulo Roberto Medeiros de Azevedo, Jenner Chrystian Veríssimo de Araújo, Josélio Maria Galvão Fernandes, José Veríssimo |
author_sort | Miranda, Cleine Aglacy Nunes |
collection | PubMed |
description | Objective. To evaluate the prevalence of HSV-1 and HSV-2 in pregnant and nonpregnant women, testing the correlation between DNA of the viruses with colposcopic and/or cytological changes, and evaluate association with sociodemographic characteristics and sexual activity. Methods. Included in this study were 106 pregnant and 130 nonpregnant women treated at primary health care units of Natal, Brazil, in the period 2010-2011. The patients were examined by colposcopy, and two cervical specimens were collected: one for cytology examination and another for analysis by PCR for detection of HSV-1 and HSV-2. Results. HSV-1 alone was detected in 16.0% of pregnant and 30.0% of nonpregnant women. For HSV-2, these rates were 12.3% and 15.5%, respectively. HSV-2 had a higher correlation with cytology and/or colposcopy changes than HSV-1 did. Genital HSV-1 infection was not associated with any of the variables tested, whereas HSV-2 infection was associated with ethnicity, marital status, and number of sexual partners. Conclusions. The prevalence of HSV-1 was higher than that observed for HSV-2 in both pregnant and nonpregnant women. The genital infection by HSV-2 was higher in women with changed colposcopy and/or cytology, and it was associated with ethnicity, marital status, and number of sexual partners. |
format | Online Article Text |
id | pubmed-3972835 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-39728352014-07-08 Genital Infection with Herpes Simplex Virus Types 1 and 2 in Women from Natal, Brazil Miranda, Cleine Aglacy Nunes Lima, Érika Galvão de Lima, Diego Breno Soares Cobucci, Ricardo Ney Oliveira Cornetta, Maria da Conceição de Mesquita Fernandes, Thales Allyrio Araújo de Medeiros de Azevedo, Paulo Roberto Medeiros de Azevedo, Jenner Chrystian Veríssimo de Araújo, Josélio Maria Galvão Fernandes, José Veríssimo ISRN Obstet Gynecol Research Article Objective. To evaluate the prevalence of HSV-1 and HSV-2 in pregnant and nonpregnant women, testing the correlation between DNA of the viruses with colposcopic and/or cytological changes, and evaluate association with sociodemographic characteristics and sexual activity. Methods. Included in this study were 106 pregnant and 130 nonpregnant women treated at primary health care units of Natal, Brazil, in the period 2010-2011. The patients were examined by colposcopy, and two cervical specimens were collected: one for cytology examination and another for analysis by PCR for detection of HSV-1 and HSV-2. Results. HSV-1 alone was detected in 16.0% of pregnant and 30.0% of nonpregnant women. For HSV-2, these rates were 12.3% and 15.5%, respectively. HSV-2 had a higher correlation with cytology and/or colposcopy changes than HSV-1 did. Genital HSV-1 infection was not associated with any of the variables tested, whereas HSV-2 infection was associated with ethnicity, marital status, and number of sexual partners. Conclusions. The prevalence of HSV-1 was higher than that observed for HSV-2 in both pregnant and nonpregnant women. The genital infection by HSV-2 was higher in women with changed colposcopy and/or cytology, and it was associated with ethnicity, marital status, and number of sexual partners. Hindawi Publishing Corporation 2014-03-11 /pmc/articles/PMC3972835/ /pubmed/25006480 http://dx.doi.org/10.1155/2014/323657 Text en Copyright © 2014 Cleine Aglacy Nunes Miranda et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Miranda, Cleine Aglacy Nunes Lima, Érika Galvão de Lima, Diego Breno Soares Cobucci, Ricardo Ney Oliveira Cornetta, Maria da Conceição de Mesquita Fernandes, Thales Allyrio Araújo de Medeiros de Azevedo, Paulo Roberto Medeiros de Azevedo, Jenner Chrystian Veríssimo de Araújo, Josélio Maria Galvão Fernandes, José Veríssimo Genital Infection with Herpes Simplex Virus Types 1 and 2 in Women from Natal, Brazil |
title | Genital Infection with Herpes Simplex Virus Types 1 and 2 in Women from Natal, Brazil |
title_full | Genital Infection with Herpes Simplex Virus Types 1 and 2 in Women from Natal, Brazil |
title_fullStr | Genital Infection with Herpes Simplex Virus Types 1 and 2 in Women from Natal, Brazil |
title_full_unstemmed | Genital Infection with Herpes Simplex Virus Types 1 and 2 in Women from Natal, Brazil |
title_short | Genital Infection with Herpes Simplex Virus Types 1 and 2 in Women from Natal, Brazil |
title_sort | genital infection with herpes simplex virus types 1 and 2 in women from natal, brazil |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972835/ https://www.ncbi.nlm.nih.gov/pubmed/25006480 http://dx.doi.org/10.1155/2014/323657 |
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