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Vitamin D3 potentiates the antitumorigenic effects of arsenic trioxide in human leukemia (HL-60) cells

BACKGROUND: Arsenic trioxide (ATO) is a novel form of therapy that has been found to aid acute promyelocytic leukemia (APL) patients. Our laboratory has demonstrated that ATO-induced cytotoxicity in human leukemia (HL-60) cells is mediated by oxidative stress. Pro-oxidants have been known to play a...

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Detalles Bibliográficos
Autores principales: Rogers, Christian S, Yedjou, Clement G, Sutton, Dwayne J, Tchounwou, Paul B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973008/
https://www.ncbi.nlm.nih.gov/pubmed/24661615
http://dx.doi.org/10.1186/2162-3619-3-9