Cargando…
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Approaches exploiting extremes of the trait distribution may reveal novel loci for common traits, but it is unknown whether such loci are generalizable to the general population. In a genome-wide search for loci associated with upper vs. lower 5(th) percentiles of body mass index, height and waist-h...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973018/ https://www.ncbi.nlm.nih.gov/pubmed/23563607 http://dx.doi.org/10.1038/ng.2606 |
_version_ | 1782309660494135296 |
---|---|
author | Berndt, Sonja I. Gustafsson, Stefan Mägi, Reedik Ganna, Andrea Wheeler, Eleanor Feitosa, Mary F. Justice, Anne E. Monda, Keri L. Croteau-Chonka, Damien C. Day, Felix R. Esko, Tõnu Fall, Tove Ferreira, Teresa Gentilini, Davide Jackson, Anne U. Luan, Jian’an Randall, Joshua C. Vedantam, Sailaja Willer, Cristen J. Winkler, Thomas W. Wood, Andrew R. Workalemahu, Tsegaselassie Hu, Yi-Juan Lee, Sang Hong Liang, Liming Lin, Dan-Yu Min, Josine L. Neale, Benjamin M. Thorleifsson, Gudmar Yang, Jian Albrecht, Eva Amin, Najaf Bragg-Gresham, Jennifer L. Cadby, Gemma den Heijer, Martin Eklund, Niina Fischer, Krista Goel, Anuj Hottenga, Jouke-Jan Huffman, Jennifer E. Jarick, Ivonne Johansson, Åsa Johnson, Toby Kanoni, Stavroula Kleber, Marcus E. König, Inke R. Kristiansson, Kati Kutalik, Zoltán Lamina, Claudia Lecoeur, Cecile Li, Guo Mangino, Massimo McArdle, Wendy L. Medina-Gomez, Carolina Müller-Nurasyid, Martina Ngwa, Julius S. Nolte, Ilja M. Paternoster, Lavinia Pechlivanis, Sonali Perola, Markus Peters, Marjolein J. Preuss, Michael Rose, Lynda M. Shi, Jianxin Shungin, Dmitry Smith, Albert Vernon Strawbridge, Rona J. Surakka, Ida Teumer, Alexander Trip, Mieke D. Tyrer, Jonathan Van Vliet-Ostaptchouk, Jana V. Vandenput, Liesbeth Waite, Lindsay L. Zhao, Jing Hua Absher, Devin Asselbergs, Folkert W. Atalay, Mustafa Attwood, Antony P. Balmforth, Anthony J. Basart, Hanneke Beilby, John Bonnycastle, Lori L. Brambilla, Paolo Bruinenberg, Marcel Campbell, Harry Chasman, Daniel I. Chines, Peter S. Collins, Francis S. Connell, John M. Cookson, William de Faire, Ulf de Vegt, Femmie Dei, Mariano Dimitriou, Maria Edkins, Sarah Estrada, Karol Evans, David M. Farrall, Martin Ferrario, Marco M. Ferrières, Jean Franke, Lude Frau, Francesca Gejman, Pablo V. Grallert, Harald Grönberg, Henrik Gudnason, Vilmundur Hall, Alistair S. Hall, Per Hartikainen, Anna-Liisa Hayward, Caroline Heard-Costa, Nancy L. Heath, Andrew C. Hebebrand, Johannes Homuth, Georg Hu, Frank B. Hunt, Sarah E. Hyppönen, Elina Iribarren, Carlos Jacobs, Kevin B. Jansson, John-Olov Jula, Antti Kähönen, Mika Kathiresan, Sekar Kee, Frank Khaw, Kay-Tee Kivimaki, Mika Koenig, Wolfgang Kraja, Aldi T. Kumari, Meena Kuulasmaa, Kari Kuusisto, Johanna Laitinen, Jaana H. Lakka, Timo A. Langenberg, Claudia Launer, Lenore J. Lind, Lars Lindström, Jaana Liu, Jianjun Liuzzi, Antonio Lokki, Marja-Liisa Lorentzon, Mattias Madden, Pamela A. Magnusson, Patrik K. Manunta, Paolo Marek, Diana März, Winfried Mateo Leach, Irene McKnight, Barbara Medland, Sarah E. Mihailov, Evelin Milani, Lili Montgomery, Grant W. Mooser, Vincent Mühleisen, Thomas W. Munroe, Patricia B. Musk, Arthur W. Narisu, Narisu Navis, Gerjan Nicholson, George Nohr, Ellen A. Ong, Ken K. Oostra, Ben A. Palmer, Colin N.A. Palotie, Aarno Peden, John F. Pedersen, Nancy Peters, Annette Polasek, Ozren Pouta, Anneli Pramstaller, Peter P. Prokopenko, Inga Pütter, Carolin Radhakrishnan, Aparna Raitakari, Olli Rendon, Augusto Rivadeneira, Fernando Rudan, Igor Saaristo, Timo E. Sambrook, Jennifer G. Sanders, Alan R. Sanna, Serena Saramies, Jouko Schipf, Sabine Schreiber, Stefan Schunkert, Heribert Shin, So-Youn Signorini, Stefano Sinisalo, Juha Skrobek, Boris Soranzo, Nicole Stančáková, Alena Stark, Klaus Stephens, Jonathan C. Stirrups, Kathleen Stolk, Ronald P. Stumvoll, Michael Swift, Amy J. Theodoraki, Eirini V. Thorand, Barbara Tregouet, David-Alexandre Tremoli, Elena Van der Klauw, Melanie M. van Meurs, Joyce B.J. Vermeulen, Sita H. Viikari, Jorma Virtamo, Jarmo Vitart, Veronique Waeber, Gérard Wang, Zhaoming Widén, Elisabeth Wild, Sarah H. Willemsen, Gonneke Winkelmann, Bernhard R. Witteman, Jacqueline C.M. Wolffenbuttel, Bruce H.R. Wong, Andrew Wright, Alan F. Zillikens, M. Carola Amouyel, Philippe Boehm, Bernhard O. Boerwinkle, Eric Boomsma, Dorret I. Caulfield, Mark J. Chanock, Stephen J. Cupples, L. Adrienne Cusi, Daniele Dedoussis, George V. Erdmann, Jeanette Eriksson, Johan G. Franks, Paul W. Froguel, Philippe Gieger, Christian Gyllensten, Ulf Hamsten, Anders Harris, Tamara B. Hengstenberg, Christian Hicks, Andrew A. Hingorani, Aroon Hinney, Anke Hofman, Albert Hovingh, Kees G. Hveem, Kristian Illig, Thomas Jarvelin, Marjo-Riitta Jöckel, Karl-Heinz Keinanen-Kiukaanniemi, Sirkka M. Kiemeney, Lambertus A. Kuh, Diana Laakso, Markku Lehtimäki, Terho Levinson, Douglas F. Martin, Nicholas G. Metspalu, Andres Morris, Andrew D. Nieminen, Markku S. Njølstad, Inger Ohlsson, Claes Oldehinkel, Albertine J. Ouwehand, Willem H. Palmer, Lyle J. Penninx, Brenda Power, Chris Province, Michael A. Psaty, Bruce M. Qi, Lu Rauramaa, Rainer Ridker, Paul M. Ripatti, Samuli Salomaa, Veikko Samani, Nilesh J. Snieder, Harold Sørensen, Thorkild I.A. Spector, Timothy D. Stefansson, Kari Tönjes, Anke Tuomilehto, Jaakko Uitterlinden, André G. Uusitupa, Matti van der Harst, Pim Vollenweider, Peter Wallaschofski, Henri Wareham, Nicholas J. Watkins, Hugh Wichmann, H.-Erich Wilson, James F. Abecasis, Goncalo R. Assimes, Themistocles L. Barroso, Inês Boehnke, Michael Borecki, Ingrid B. Deloukas, Panos Fox, Caroline S. Frayling, Timothy Groop, Leif C. Haritunian, Talin Heid, Iris M. Hunter, David Kaplan, Robert C. Karpe, Fredrik Moffatt, Miriam Mohlke, Karen L. O’Connell, Jeffrey R. Pawitan, Yudi Schadt, Eric E. Schlessinger, David Steinthorsdottir, Valgerdur Strachan, David P. Thorsteinsdottir, Unnur van Duijn, Cornelia M. Visscher, Peter M. Di Blasio, Anna Maria Hirschhorn, Joel N. Lindgren, Cecilia M. Morris, Andrew P. Meyre, David Scherag, André McCarthy, Mark I. Speliotes, Elizabeth K. North, Kari E. Loos, Ruth J.F. Ingelsson, Erik |
author_facet | Berndt, Sonja I. Gustafsson, Stefan Mägi, Reedik Ganna, Andrea Wheeler, Eleanor Feitosa, Mary F. Justice, Anne E. Monda, Keri L. Croteau-Chonka, Damien C. Day, Felix R. Esko, Tõnu Fall, Tove Ferreira, Teresa Gentilini, Davide Jackson, Anne U. Luan, Jian’an Randall, Joshua C. Vedantam, Sailaja Willer, Cristen J. Winkler, Thomas W. Wood, Andrew R. Workalemahu, Tsegaselassie Hu, Yi-Juan Lee, Sang Hong Liang, Liming Lin, Dan-Yu Min, Josine L. Neale, Benjamin M. Thorleifsson, Gudmar Yang, Jian Albrecht, Eva Amin, Najaf Bragg-Gresham, Jennifer L. Cadby, Gemma den Heijer, Martin Eklund, Niina Fischer, Krista Goel, Anuj Hottenga, Jouke-Jan Huffman, Jennifer E. Jarick, Ivonne Johansson, Åsa Johnson, Toby Kanoni, Stavroula Kleber, Marcus E. König, Inke R. Kristiansson, Kati Kutalik, Zoltán Lamina, Claudia Lecoeur, Cecile Li, Guo Mangino, Massimo McArdle, Wendy L. Medina-Gomez, Carolina Müller-Nurasyid, Martina Ngwa, Julius S. Nolte, Ilja M. Paternoster, Lavinia Pechlivanis, Sonali Perola, Markus Peters, Marjolein J. Preuss, Michael Rose, Lynda M. Shi, Jianxin Shungin, Dmitry Smith, Albert Vernon Strawbridge, Rona J. Surakka, Ida Teumer, Alexander Trip, Mieke D. Tyrer, Jonathan Van Vliet-Ostaptchouk, Jana V. Vandenput, Liesbeth Waite, Lindsay L. Zhao, Jing Hua Absher, Devin Asselbergs, Folkert W. Atalay, Mustafa Attwood, Antony P. Balmforth, Anthony J. Basart, Hanneke Beilby, John Bonnycastle, Lori L. Brambilla, Paolo Bruinenberg, Marcel Campbell, Harry Chasman, Daniel I. Chines, Peter S. Collins, Francis S. Connell, John M. Cookson, William de Faire, Ulf de Vegt, Femmie Dei, Mariano Dimitriou, Maria Edkins, Sarah Estrada, Karol Evans, David M. Farrall, Martin Ferrario, Marco M. Ferrières, Jean Franke, Lude Frau, Francesca Gejman, Pablo V. Grallert, Harald Grönberg, Henrik Gudnason, Vilmundur Hall, Alistair S. Hall, Per Hartikainen, Anna-Liisa Hayward, Caroline Heard-Costa, Nancy L. Heath, Andrew C. Hebebrand, Johannes Homuth, Georg Hu, Frank B. Hunt, Sarah E. Hyppönen, Elina Iribarren, Carlos Jacobs, Kevin B. Jansson, John-Olov Jula, Antti Kähönen, Mika Kathiresan, Sekar Kee, Frank Khaw, Kay-Tee Kivimaki, Mika Koenig, Wolfgang Kraja, Aldi T. Kumari, Meena Kuulasmaa, Kari Kuusisto, Johanna Laitinen, Jaana H. Lakka, Timo A. Langenberg, Claudia Launer, Lenore J. Lind, Lars Lindström, Jaana Liu, Jianjun Liuzzi, Antonio Lokki, Marja-Liisa Lorentzon, Mattias Madden, Pamela A. Magnusson, Patrik K. Manunta, Paolo Marek, Diana März, Winfried Mateo Leach, Irene McKnight, Barbara Medland, Sarah E. Mihailov, Evelin Milani, Lili Montgomery, Grant W. Mooser, Vincent Mühleisen, Thomas W. Munroe, Patricia B. Musk, Arthur W. Narisu, Narisu Navis, Gerjan Nicholson, George Nohr, Ellen A. Ong, Ken K. Oostra, Ben A. Palmer, Colin N.A. Palotie, Aarno Peden, John F. Pedersen, Nancy Peters, Annette Polasek, Ozren Pouta, Anneli Pramstaller, Peter P. Prokopenko, Inga Pütter, Carolin Radhakrishnan, Aparna Raitakari, Olli Rendon, Augusto Rivadeneira, Fernando Rudan, Igor Saaristo, Timo E. Sambrook, Jennifer G. Sanders, Alan R. Sanna, Serena Saramies, Jouko Schipf, Sabine Schreiber, Stefan Schunkert, Heribert Shin, So-Youn Signorini, Stefano Sinisalo, Juha Skrobek, Boris Soranzo, Nicole Stančáková, Alena Stark, Klaus Stephens, Jonathan C. Stirrups, Kathleen Stolk, Ronald P. Stumvoll, Michael Swift, Amy J. Theodoraki, Eirini V. Thorand, Barbara Tregouet, David-Alexandre Tremoli, Elena Van der Klauw, Melanie M. van Meurs, Joyce B.J. Vermeulen, Sita H. Viikari, Jorma Virtamo, Jarmo Vitart, Veronique Waeber, Gérard Wang, Zhaoming Widén, Elisabeth Wild, Sarah H. Willemsen, Gonneke Winkelmann, Bernhard R. Witteman, Jacqueline C.M. Wolffenbuttel, Bruce H.R. Wong, Andrew Wright, Alan F. Zillikens, M. Carola Amouyel, Philippe Boehm, Bernhard O. Boerwinkle, Eric Boomsma, Dorret I. Caulfield, Mark J. Chanock, Stephen J. Cupples, L. Adrienne Cusi, Daniele Dedoussis, George V. Erdmann, Jeanette Eriksson, Johan G. Franks, Paul W. Froguel, Philippe Gieger, Christian Gyllensten, Ulf Hamsten, Anders Harris, Tamara B. Hengstenberg, Christian Hicks, Andrew A. Hingorani, Aroon Hinney, Anke Hofman, Albert Hovingh, Kees G. Hveem, Kristian Illig, Thomas Jarvelin, Marjo-Riitta Jöckel, Karl-Heinz Keinanen-Kiukaanniemi, Sirkka M. Kiemeney, Lambertus A. Kuh, Diana Laakso, Markku Lehtimäki, Terho Levinson, Douglas F. Martin, Nicholas G. Metspalu, Andres Morris, Andrew D. Nieminen, Markku S. Njølstad, Inger Ohlsson, Claes Oldehinkel, Albertine J. Ouwehand, Willem H. Palmer, Lyle J. Penninx, Brenda Power, Chris Province, Michael A. Psaty, Bruce M. Qi, Lu Rauramaa, Rainer Ridker, Paul M. Ripatti, Samuli Salomaa, Veikko Samani, Nilesh J. Snieder, Harold Sørensen, Thorkild I.A. Spector, Timothy D. Stefansson, Kari Tönjes, Anke Tuomilehto, Jaakko Uitterlinden, André G. Uusitupa, Matti van der Harst, Pim Vollenweider, Peter Wallaschofski, Henri Wareham, Nicholas J. Watkins, Hugh Wichmann, H.-Erich Wilson, James F. Abecasis, Goncalo R. Assimes, Themistocles L. Barroso, Inês Boehnke, Michael Borecki, Ingrid B. Deloukas, Panos Fox, Caroline S. Frayling, Timothy Groop, Leif C. Haritunian, Talin Heid, Iris M. Hunter, David Kaplan, Robert C. Karpe, Fredrik Moffatt, Miriam Mohlke, Karen L. O’Connell, Jeffrey R. Pawitan, Yudi Schadt, Eric E. Schlessinger, David Steinthorsdottir, Valgerdur Strachan, David P. Thorsteinsdottir, Unnur van Duijn, Cornelia M. Visscher, Peter M. Di Blasio, Anna Maria Hirschhorn, Joel N. Lindgren, Cecilia M. Morris, Andrew P. Meyre, David Scherag, André McCarthy, Mark I. Speliotes, Elizabeth K. North, Kari E. Loos, Ruth J.F. Ingelsson, Erik |
author_sort | Berndt, Sonja I. |
collection | PubMed |
description | Approaches exploiting extremes of the trait distribution may reveal novel loci for common traits, but it is unknown whether such loci are generalizable to the general population. In a genome-wide search for loci associated with upper vs. lower 5(th) percentiles of body mass index, height and waist-hip ratio, as well as clinical classes of obesity including up to 263,407 European individuals, we identified four new loci (IGFBP4, H6PD, RSRC1, PPP2R2A) influencing height detected in the tails and seven new loci (HNF4G, RPTOR, GNAT2, MRPS33P4, ADCY9, HS6ST3, ZZZ3) for clinical classes of obesity. Further, we show that there is large overlap in terms of genetic structure and distribution of variants between traits based on extremes and the general population and little etiologic heterogeneity between obesity subgroups. |
format | Online Article Text |
id | pubmed-3973018 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
record_format | MEDLINE/PubMed |
spelling | pubmed-39730182014-04-02 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture Berndt, Sonja I. Gustafsson, Stefan Mägi, Reedik Ganna, Andrea Wheeler, Eleanor Feitosa, Mary F. Justice, Anne E. Monda, Keri L. Croteau-Chonka, Damien C. Day, Felix R. Esko, Tõnu Fall, Tove Ferreira, Teresa Gentilini, Davide Jackson, Anne U. Luan, Jian’an Randall, Joshua C. Vedantam, Sailaja Willer, Cristen J. Winkler, Thomas W. Wood, Andrew R. Workalemahu, Tsegaselassie Hu, Yi-Juan Lee, Sang Hong Liang, Liming Lin, Dan-Yu Min, Josine L. Neale, Benjamin M. Thorleifsson, Gudmar Yang, Jian Albrecht, Eva Amin, Najaf Bragg-Gresham, Jennifer L. Cadby, Gemma den Heijer, Martin Eklund, Niina Fischer, Krista Goel, Anuj Hottenga, Jouke-Jan Huffman, Jennifer E. Jarick, Ivonne Johansson, Åsa Johnson, Toby Kanoni, Stavroula Kleber, Marcus E. König, Inke R. Kristiansson, Kati Kutalik, Zoltán Lamina, Claudia Lecoeur, Cecile Li, Guo Mangino, Massimo McArdle, Wendy L. Medina-Gomez, Carolina Müller-Nurasyid, Martina Ngwa, Julius S. Nolte, Ilja M. Paternoster, Lavinia Pechlivanis, Sonali Perola, Markus Peters, Marjolein J. Preuss, Michael Rose, Lynda M. Shi, Jianxin Shungin, Dmitry Smith, Albert Vernon Strawbridge, Rona J. Surakka, Ida Teumer, Alexander Trip, Mieke D. Tyrer, Jonathan Van Vliet-Ostaptchouk, Jana V. Vandenput, Liesbeth Waite, Lindsay L. Zhao, Jing Hua Absher, Devin Asselbergs, Folkert W. Atalay, Mustafa Attwood, Antony P. Balmforth, Anthony J. Basart, Hanneke Beilby, John Bonnycastle, Lori L. Brambilla, Paolo Bruinenberg, Marcel Campbell, Harry Chasman, Daniel I. Chines, Peter S. Collins, Francis S. Connell, John M. Cookson, William de Faire, Ulf de Vegt, Femmie Dei, Mariano Dimitriou, Maria Edkins, Sarah Estrada, Karol Evans, David M. Farrall, Martin Ferrario, Marco M. Ferrières, Jean Franke, Lude Frau, Francesca Gejman, Pablo V. Grallert, Harald Grönberg, Henrik Gudnason, Vilmundur Hall, Alistair S. Hall, Per Hartikainen, Anna-Liisa Hayward, Caroline Heard-Costa, Nancy L. Heath, Andrew C. Hebebrand, Johannes Homuth, Georg Hu, Frank B. Hunt, Sarah E. Hyppönen, Elina Iribarren, Carlos Jacobs, Kevin B. Jansson, John-Olov Jula, Antti Kähönen, Mika Kathiresan, Sekar Kee, Frank Khaw, Kay-Tee Kivimaki, Mika Koenig, Wolfgang Kraja, Aldi T. Kumari, Meena Kuulasmaa, Kari Kuusisto, Johanna Laitinen, Jaana H. Lakka, Timo A. Langenberg, Claudia Launer, Lenore J. Lind, Lars Lindström, Jaana Liu, Jianjun Liuzzi, Antonio Lokki, Marja-Liisa Lorentzon, Mattias Madden, Pamela A. Magnusson, Patrik K. Manunta, Paolo Marek, Diana März, Winfried Mateo Leach, Irene McKnight, Barbara Medland, Sarah E. Mihailov, Evelin Milani, Lili Montgomery, Grant W. Mooser, Vincent Mühleisen, Thomas W. Munroe, Patricia B. Musk, Arthur W. Narisu, Narisu Navis, Gerjan Nicholson, George Nohr, Ellen A. Ong, Ken K. Oostra, Ben A. Palmer, Colin N.A. Palotie, Aarno Peden, John F. Pedersen, Nancy Peters, Annette Polasek, Ozren Pouta, Anneli Pramstaller, Peter P. Prokopenko, Inga Pütter, Carolin Radhakrishnan, Aparna Raitakari, Olli Rendon, Augusto Rivadeneira, Fernando Rudan, Igor Saaristo, Timo E. Sambrook, Jennifer G. Sanders, Alan R. Sanna, Serena Saramies, Jouko Schipf, Sabine Schreiber, Stefan Schunkert, Heribert Shin, So-Youn Signorini, Stefano Sinisalo, Juha Skrobek, Boris Soranzo, Nicole Stančáková, Alena Stark, Klaus Stephens, Jonathan C. Stirrups, Kathleen Stolk, Ronald P. Stumvoll, Michael Swift, Amy J. Theodoraki, Eirini V. Thorand, Barbara Tregouet, David-Alexandre Tremoli, Elena Van der Klauw, Melanie M. van Meurs, Joyce B.J. Vermeulen, Sita H. Viikari, Jorma Virtamo, Jarmo Vitart, Veronique Waeber, Gérard Wang, Zhaoming Widén, Elisabeth Wild, Sarah H. Willemsen, Gonneke Winkelmann, Bernhard R. Witteman, Jacqueline C.M. Wolffenbuttel, Bruce H.R. Wong, Andrew Wright, Alan F. Zillikens, M. Carola Amouyel, Philippe Boehm, Bernhard O. Boerwinkle, Eric Boomsma, Dorret I. Caulfield, Mark J. Chanock, Stephen J. Cupples, L. Adrienne Cusi, Daniele Dedoussis, George V. Erdmann, Jeanette Eriksson, Johan G. Franks, Paul W. Froguel, Philippe Gieger, Christian Gyllensten, Ulf Hamsten, Anders Harris, Tamara B. Hengstenberg, Christian Hicks, Andrew A. Hingorani, Aroon Hinney, Anke Hofman, Albert Hovingh, Kees G. Hveem, Kristian Illig, Thomas Jarvelin, Marjo-Riitta Jöckel, Karl-Heinz Keinanen-Kiukaanniemi, Sirkka M. Kiemeney, Lambertus A. Kuh, Diana Laakso, Markku Lehtimäki, Terho Levinson, Douglas F. Martin, Nicholas G. Metspalu, Andres Morris, Andrew D. Nieminen, Markku S. Njølstad, Inger Ohlsson, Claes Oldehinkel, Albertine J. Ouwehand, Willem H. Palmer, Lyle J. Penninx, Brenda Power, Chris Province, Michael A. Psaty, Bruce M. Qi, Lu Rauramaa, Rainer Ridker, Paul M. Ripatti, Samuli Salomaa, Veikko Samani, Nilesh J. Snieder, Harold Sørensen, Thorkild I.A. Spector, Timothy D. Stefansson, Kari Tönjes, Anke Tuomilehto, Jaakko Uitterlinden, André G. Uusitupa, Matti van der Harst, Pim Vollenweider, Peter Wallaschofski, Henri Wareham, Nicholas J. Watkins, Hugh Wichmann, H.-Erich Wilson, James F. Abecasis, Goncalo R. Assimes, Themistocles L. Barroso, Inês Boehnke, Michael Borecki, Ingrid B. Deloukas, Panos Fox, Caroline S. Frayling, Timothy Groop, Leif C. Haritunian, Talin Heid, Iris M. Hunter, David Kaplan, Robert C. Karpe, Fredrik Moffatt, Miriam Mohlke, Karen L. O’Connell, Jeffrey R. Pawitan, Yudi Schadt, Eric E. Schlessinger, David Steinthorsdottir, Valgerdur Strachan, David P. Thorsteinsdottir, Unnur van Duijn, Cornelia M. Visscher, Peter M. Di Blasio, Anna Maria Hirschhorn, Joel N. Lindgren, Cecilia M. Morris, Andrew P. Meyre, David Scherag, André McCarthy, Mark I. Speliotes, Elizabeth K. North, Kari E. Loos, Ruth J.F. Ingelsson, Erik Nat Genet Article Approaches exploiting extremes of the trait distribution may reveal novel loci for common traits, but it is unknown whether such loci are generalizable to the general population. In a genome-wide search for loci associated with upper vs. lower 5(th) percentiles of body mass index, height and waist-hip ratio, as well as clinical classes of obesity including up to 263,407 European individuals, we identified four new loci (IGFBP4, H6PD, RSRC1, PPP2R2A) influencing height detected in the tails and seven new loci (HNF4G, RPTOR, GNAT2, MRPS33P4, ADCY9, HS6ST3, ZZZ3) for clinical classes of obesity. Further, we show that there is large overlap in terms of genetic structure and distribution of variants between traits based on extremes and the general population and little etiologic heterogeneity between obesity subgroups. 2013-04-07 2013-05 /pmc/articles/PMC3973018/ /pubmed/23563607 http://dx.doi.org/10.1038/ng.2606 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms |
spellingShingle | Article Berndt, Sonja I. Gustafsson, Stefan Mägi, Reedik Ganna, Andrea Wheeler, Eleanor Feitosa, Mary F. Justice, Anne E. Monda, Keri L. Croteau-Chonka, Damien C. Day, Felix R. Esko, Tõnu Fall, Tove Ferreira, Teresa Gentilini, Davide Jackson, Anne U. Luan, Jian’an Randall, Joshua C. Vedantam, Sailaja Willer, Cristen J. Winkler, Thomas W. Wood, Andrew R. Workalemahu, Tsegaselassie Hu, Yi-Juan Lee, Sang Hong Liang, Liming Lin, Dan-Yu Min, Josine L. Neale, Benjamin M. Thorleifsson, Gudmar Yang, Jian Albrecht, Eva Amin, Najaf Bragg-Gresham, Jennifer L. Cadby, Gemma den Heijer, Martin Eklund, Niina Fischer, Krista Goel, Anuj Hottenga, Jouke-Jan Huffman, Jennifer E. Jarick, Ivonne Johansson, Åsa Johnson, Toby Kanoni, Stavroula Kleber, Marcus E. König, Inke R. Kristiansson, Kati Kutalik, Zoltán Lamina, Claudia Lecoeur, Cecile Li, Guo Mangino, Massimo McArdle, Wendy L. Medina-Gomez, Carolina Müller-Nurasyid, Martina Ngwa, Julius S. Nolte, Ilja M. Paternoster, Lavinia Pechlivanis, Sonali Perola, Markus Peters, Marjolein J. Preuss, Michael Rose, Lynda M. Shi, Jianxin Shungin, Dmitry Smith, Albert Vernon Strawbridge, Rona J. Surakka, Ida Teumer, Alexander Trip, Mieke D. Tyrer, Jonathan Van Vliet-Ostaptchouk, Jana V. Vandenput, Liesbeth Waite, Lindsay L. Zhao, Jing Hua Absher, Devin Asselbergs, Folkert W. Atalay, Mustafa Attwood, Antony P. Balmforth, Anthony J. Basart, Hanneke Beilby, John Bonnycastle, Lori L. Brambilla, Paolo Bruinenberg, Marcel Campbell, Harry Chasman, Daniel I. Chines, Peter S. Collins, Francis S. Connell, John M. Cookson, William de Faire, Ulf de Vegt, Femmie Dei, Mariano Dimitriou, Maria Edkins, Sarah Estrada, Karol Evans, David M. Farrall, Martin Ferrario, Marco M. Ferrières, Jean Franke, Lude Frau, Francesca Gejman, Pablo V. Grallert, Harald Grönberg, Henrik Gudnason, Vilmundur Hall, Alistair S. Hall, Per Hartikainen, Anna-Liisa Hayward, Caroline Heard-Costa, Nancy L. Heath, Andrew C. Hebebrand, Johannes Homuth, Georg Hu, Frank B. Hunt, Sarah E. Hyppönen, Elina Iribarren, Carlos Jacobs, Kevin B. Jansson, John-Olov Jula, Antti Kähönen, Mika Kathiresan, Sekar Kee, Frank Khaw, Kay-Tee Kivimaki, Mika Koenig, Wolfgang Kraja, Aldi T. Kumari, Meena Kuulasmaa, Kari Kuusisto, Johanna Laitinen, Jaana H. Lakka, Timo A. Langenberg, Claudia Launer, Lenore J. Lind, Lars Lindström, Jaana Liu, Jianjun Liuzzi, Antonio Lokki, Marja-Liisa Lorentzon, Mattias Madden, Pamela A. Magnusson, Patrik K. Manunta, Paolo Marek, Diana März, Winfried Mateo Leach, Irene McKnight, Barbara Medland, Sarah E. Mihailov, Evelin Milani, Lili Montgomery, Grant W. Mooser, Vincent Mühleisen, Thomas W. Munroe, Patricia B. Musk, Arthur W. Narisu, Narisu Navis, Gerjan Nicholson, George Nohr, Ellen A. Ong, Ken K. Oostra, Ben A. Palmer, Colin N.A. Palotie, Aarno Peden, John F. Pedersen, Nancy Peters, Annette Polasek, Ozren Pouta, Anneli Pramstaller, Peter P. Prokopenko, Inga Pütter, Carolin Radhakrishnan, Aparna Raitakari, Olli Rendon, Augusto Rivadeneira, Fernando Rudan, Igor Saaristo, Timo E. Sambrook, Jennifer G. Sanders, Alan R. Sanna, Serena Saramies, Jouko Schipf, Sabine Schreiber, Stefan Schunkert, Heribert Shin, So-Youn Signorini, Stefano Sinisalo, Juha Skrobek, Boris Soranzo, Nicole Stančáková, Alena Stark, Klaus Stephens, Jonathan C. Stirrups, Kathleen Stolk, Ronald P. Stumvoll, Michael Swift, Amy J. Theodoraki, Eirini V. Thorand, Barbara Tregouet, David-Alexandre Tremoli, Elena Van der Klauw, Melanie M. van Meurs, Joyce B.J. Vermeulen, Sita H. Viikari, Jorma Virtamo, Jarmo Vitart, Veronique Waeber, Gérard Wang, Zhaoming Widén, Elisabeth Wild, Sarah H. Willemsen, Gonneke Winkelmann, Bernhard R. Witteman, Jacqueline C.M. Wolffenbuttel, Bruce H.R. Wong, Andrew Wright, Alan F. Zillikens, M. Carola Amouyel, Philippe Boehm, Bernhard O. Boerwinkle, Eric Boomsma, Dorret I. Caulfield, Mark J. Chanock, Stephen J. Cupples, L. Adrienne Cusi, Daniele Dedoussis, George V. Erdmann, Jeanette Eriksson, Johan G. Franks, Paul W. Froguel, Philippe Gieger, Christian Gyllensten, Ulf Hamsten, Anders Harris, Tamara B. Hengstenberg, Christian Hicks, Andrew A. Hingorani, Aroon Hinney, Anke Hofman, Albert Hovingh, Kees G. Hveem, Kristian Illig, Thomas Jarvelin, Marjo-Riitta Jöckel, Karl-Heinz Keinanen-Kiukaanniemi, Sirkka M. Kiemeney, Lambertus A. Kuh, Diana Laakso, Markku Lehtimäki, Terho Levinson, Douglas F. Martin, Nicholas G. Metspalu, Andres Morris, Andrew D. Nieminen, Markku S. Njølstad, Inger Ohlsson, Claes Oldehinkel, Albertine J. Ouwehand, Willem H. Palmer, Lyle J. Penninx, Brenda Power, Chris Province, Michael A. Psaty, Bruce M. Qi, Lu Rauramaa, Rainer Ridker, Paul M. Ripatti, Samuli Salomaa, Veikko Samani, Nilesh J. Snieder, Harold Sørensen, Thorkild I.A. Spector, Timothy D. Stefansson, Kari Tönjes, Anke Tuomilehto, Jaakko Uitterlinden, André G. Uusitupa, Matti van der Harst, Pim Vollenweider, Peter Wallaschofski, Henri Wareham, Nicholas J. Watkins, Hugh Wichmann, H.-Erich Wilson, James F. Abecasis, Goncalo R. Assimes, Themistocles L. Barroso, Inês Boehnke, Michael Borecki, Ingrid B. Deloukas, Panos Fox, Caroline S. Frayling, Timothy Groop, Leif C. Haritunian, Talin Heid, Iris M. Hunter, David Kaplan, Robert C. Karpe, Fredrik Moffatt, Miriam Mohlke, Karen L. O’Connell, Jeffrey R. Pawitan, Yudi Schadt, Eric E. Schlessinger, David Steinthorsdottir, Valgerdur Strachan, David P. Thorsteinsdottir, Unnur van Duijn, Cornelia M. Visscher, Peter M. Di Blasio, Anna Maria Hirschhorn, Joel N. Lindgren, Cecilia M. Morris, Andrew P. Meyre, David Scherag, André McCarthy, Mark I. Speliotes, Elizabeth K. North, Kari E. Loos, Ruth J.F. Ingelsson, Erik Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture |
title | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture |
title_full | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture |
title_fullStr | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture |
title_full_unstemmed | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture |
title_short | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture |
title_sort | genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973018/ https://www.ncbi.nlm.nih.gov/pubmed/23563607 http://dx.doi.org/10.1038/ng.2606 |
work_keys_str_mv | AT berndtsonjai genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT gustafssonstefan genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT magireedik genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT gannaandrea genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT wheelereleanor genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT feitosamaryf genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT justiceannee genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT mondakeril genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT croteauchonkadamienc genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT dayfelixr genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT eskotonu genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT falltove genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT ferreirateresa genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT gentilinidavide genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT jacksonanneu genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT luanjianan genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT randalljoshuac genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT vedantamsailaja genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT willercristenj genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT winklerthomasw genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT woodandrewr genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT workalemahutsegaselassie genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT huyijuan genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT leesanghong genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT liangliming genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT lindanyu genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT minjosinel genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT nealebenjaminm genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT thorleifssongudmar genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT yangjian genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT albrechteva genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT aminnajaf genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT bragggreshamjenniferl genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT cadbygemma genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT denheijermartin genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT eklundniina genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT fischerkrista genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT goelanuj genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT hottengajoukejan genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT huffmanjennifere genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT jarickivonne genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT johanssonasa genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT johnsontoby genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT kanonistavroula genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT klebermarcuse genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT koniginker genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT kristianssonkati genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT kutalikzoltan genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT laminaclaudia genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT lecoeurcecile genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT liguo genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT manginomassimo genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT mcardlewendyl genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT medinagomezcarolina genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT mullernurasyidmartina genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT ngwajuliuss genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT nolteiljam genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT paternosterlavinia genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT pechlivanissonali genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT perolamarkus genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT petersmarjoleinj genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT preussmichael genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT roselyndam genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT shijianxin genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT shungindmitry genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT smithalbertvernon genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT strawbridgeronaj genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT surakkaida genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT teumeralexander genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT tripmieked genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT tyrerjonathan genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT vanvlietostaptchoukjanav genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT vandenputliesbeth genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT waitelindsayl genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT zhaojinghua genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT absherdevin genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT asselbergsfolkertw genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT atalaymustafa genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT attwoodantonyp genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT balmforthanthonyj genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT basarthanneke genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT beilbyjohn genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT bonnycastleloril genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT brambillapaolo genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT bruinenbergmarcel genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT campbellharry genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT chasmandanieli genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT chinespeters genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT collinsfranciss genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT connelljohnm genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT cooksonwilliam genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT defaireulf genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT devegtfemmie genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT deimariano genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT dimitrioumaria genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT edkinssarah genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT estradakarol genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT evansdavidm genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT farrallmartin genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT ferrariomarcom genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT ferrieresjean genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT frankelude genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT fraufrancesca genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT gejmanpablov genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT grallertharald genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT gronberghenrik genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT gudnasonvilmundur genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT hallalistairs genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT hallper genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT hartikainenannaliisa genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT haywardcaroline genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT heardcostanancyl genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT heathandrewc genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT hebebrandjohannes genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT homuthgeorg genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT hufrankb genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT huntsarahe genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT hypponenelina genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT iribarrencarlos genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT jacobskevinb genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT janssonjohnolov genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT julaantti genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT kahonenmika genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT kathiresansekar genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT keefrank genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT khawkaytee genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT kivimakimika genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT koenigwolfgang genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT krajaaldit genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT kumarimeena genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT kuulasmaakari genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT kuusistojohanna genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT laitinenjaanah genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT lakkatimoa genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT langenbergclaudia genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT launerlenorej genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT lindlars genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT lindstromjaana genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT liujianjun genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT liuzziantonio genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT lokkimarjaliisa genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT lorentzonmattias genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT maddenpamelaa genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT magnussonpatrikk genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT manuntapaolo genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT marekdiana genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT marzwinfried genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT mateoleachirene genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT mcknightbarbara genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT medlandsarahe genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT mihailovevelin genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT milanilili genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT montgomerygrantw genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT mooservincent genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT muhleisenthomasw genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT munroepatriciab genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT muskarthurw genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT narisunarisu genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT navisgerjan genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT nicholsongeorge genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT nohrellena genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT ongkenk genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT oostrabena genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT palmercolinna genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT palotieaarno genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT pedenjohnf genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT pedersennancy genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT petersannette genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT polasekozren genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT poutaanneli genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT pramstallerpeterp genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT prokopenkoinga genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT puttercarolin genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT radhakrishnanaparna genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT raitakariolli genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT rendonaugusto genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT rivadeneirafernando genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT rudanigor genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT saaristotimoe genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT sambrookjenniferg genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT sandersalanr genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT sannaserena genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT saramiesjouko genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT schipfsabine genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT schreiberstefan genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT schunkertheribert genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT shinsoyoun genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT signorinistefano genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT sinisalojuha genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT skrobekboris genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT soranzonicole genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT stancakovaalena genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT starkklaus genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT stephensjonathanc genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT stirrupskathleen genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT stolkronaldp genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT stumvollmichael genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT swiftamyj genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT theodorakieiriniv genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT thorandbarbara genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT tregouetdavidalexandre genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT tremolielena genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT vanderklauwmelaniem genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT vanmeursjoycebj genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT vermeulensitah genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT viikarijorma genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT virtamojarmo genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT vitartveronique genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT waebergerard genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT wangzhaoming genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT widenelisabeth genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT wildsarahh genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT willemsengonneke genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT winkelmannbernhardr genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT wittemanjacquelinecm genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT wolffenbuttelbrucehr genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT wongandrew genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT wrightalanf genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT zillikensmcarola genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT amouyelphilippe genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT boehmbernhardo genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT boerwinkleeric genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT boomsmadorreti genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT caulfieldmarkj genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT chanockstephenj genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT cupplesladrienne genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT cusidaniele genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT dedoussisgeorgev genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT erdmannjeanette genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT erikssonjohang genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT frankspaulw genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT froguelphilippe genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT giegerchristian genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT gyllenstenulf genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT hamstenanders genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT harristamarab genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT hengstenbergchristian genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT hicksandrewa genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT hingoraniaroon genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT hinneyanke genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT hofmanalbert genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT hovinghkeesg genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT hveemkristian genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT illigthomas genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT jarvelinmarjoriitta genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT jockelkarlheinz genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT keinanenkiukaanniemisirkkam genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT kiemeneylambertusa genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT kuhdiana genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT laaksomarkku genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT lehtimakiterho genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT levinsondouglasf genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT martinnicholasg genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT metspaluandres genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT morrisandrewd genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT nieminenmarkkus genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT njølstadinger genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT ohlssonclaes genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT oldehinkelalbertinej genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT ouwehandwillemh genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT palmerlylej genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT penninxbrenda genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT powerchris genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT provincemichaela genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT psatybrucem genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT qilu genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT rauramaarainer genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT ridkerpaulm genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT ripattisamuli genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT salomaaveikko genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT samaninileshj genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT sniederharold genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT sørensenthorkildia genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT spectortimothyd genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT stefanssonkari genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT tonjesanke genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT tuomilehtojaakko genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT uitterlindenandreg genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT uusitupamatti genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT vanderharstpim genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT vollenweiderpeter genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT wallaschofskihenri genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT warehamnicholasj genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT watkinshugh genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT wichmannherich genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT wilsonjamesf genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT abecasisgoncalor genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT assimesthemistoclesl genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT barrosoines genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT boehnkemichael genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT boreckiingridb genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT deloukaspanos genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT foxcarolines genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT fraylingtimothy genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT groopleifc genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT harituniantalin genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT heidirism genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT hunterdavid genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT kaplanrobertc genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT karpefredrik genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT moffattmiriam genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT mohlkekarenl genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT oconnelljeffreyr genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT pawitanyudi genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT schadterice genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT schlessingerdavid genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT steinthorsdottirvalgerdur genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT strachandavidp genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT thorsteinsdottirunnur genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT vanduijncorneliam genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT visscherpeterm genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT diblasioannamaria genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT hirschhornjoeln genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT lindgrenceciliam genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT morrisandrewp genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT meyredavid genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT scheragandre genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT mccarthymarki genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT spelioteselizabethk genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT northkarie genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT loosruthjf genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture AT ingelssonerik genomewidemetaanalysisidentifies11newlociforanthropometrictraitsandprovidesinsightsintogeneticarchitecture |