A FSH-Secreting Pituitary Macroadenoma Causing A Testosterone Deficiency Syndrome

FSH-secreting pituitary adenomas can affect sexual and reproductive function. In this article, we have reported the case of a 32-year-old male with secondary infertility. The patient had sexual and reproductive disturbances. The test results of the blood samples indicated obviously decreased testost...

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Autores principales: Wang, Xiong, Ge, Li, Cui, Yuanqing, Lang, Cuihong, Hao, Cuifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973166/
https://www.ncbi.nlm.nih.gov/pubmed/24696774
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author Wang, Xiong
Ge, Li
Cui, Yuanqing
Lang, Cuihong
Hao, Cuifang
author_facet Wang, Xiong
Ge, Li
Cui, Yuanqing
Lang, Cuihong
Hao, Cuifang
author_sort Wang, Xiong
collection PubMed
description FSH-secreting pituitary adenomas can affect sexual and reproductive function. In this article, we have reported the case of a 32-year-old male with secondary infertility. The patient had sexual and reproductive disturbances. The test results of the blood samples indicated obviously decreased testosterone (T) and estradiol (E2) levels. Based on previous hormonal results, the patient received pituitary stimulation and human chorionic gonadotropin (hCG) tests. Both follicle stimulating hormone (FSH) and luteinizing hormone (LH) showed low response during the pituitary stimulation test. The results of the hCG test indicated that T/E2 could recover to a normal level. In addition, this patient was diagnosed with pituitary macroadenoma, which was supported by the pituitary MRI. The man’s sexual and reproductive functions recovered following surgery. The pathological results confirmed that the tumor tissue was an FSH-secreting pituitary adenoma by immunohistochemical staining. The purpose of this report was to review the relative literature and discuss the influence of FSH-secreting pituitary adenomas on hormones through the hypothalamus-pituitary-testis axis.
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spelling pubmed-39731662014-04-02 A FSH-Secreting Pituitary Macroadenoma Causing A Testosterone Deficiency Syndrome Wang, Xiong Ge, Li Cui, Yuanqing Lang, Cuihong Hao, Cuifang Int J Fertil Steril Case Report FSH-secreting pituitary adenomas can affect sexual and reproductive function. In this article, we have reported the case of a 32-year-old male with secondary infertility. The patient had sexual and reproductive disturbances. The test results of the blood samples indicated obviously decreased testosterone (T) and estradiol (E2) levels. Based on previous hormonal results, the patient received pituitary stimulation and human chorionic gonadotropin (hCG) tests. Both follicle stimulating hormone (FSH) and luteinizing hormone (LH) showed low response during the pituitary stimulation test. The results of the hCG test indicated that T/E2 could recover to a normal level. In addition, this patient was diagnosed with pituitary macroadenoma, which was supported by the pituitary MRI. The man’s sexual and reproductive functions recovered following surgery. The pathological results confirmed that the tumor tissue was an FSH-secreting pituitary adenoma by immunohistochemical staining. The purpose of this report was to review the relative literature and discuss the influence of FSH-secreting pituitary adenomas on hormones through the hypothalamus-pituitary-testis axis. Royan Institute 2014 2014-03-09 /pmc/articles/PMC3973166/ /pubmed/24696774 Text en Any use, distribution, reproduction or abstract of this publication in any medium, with the exception of commercial purposes, is permitted provided the original work is properly cited http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Wang, Xiong
Ge, Li
Cui, Yuanqing
Lang, Cuihong
Hao, Cuifang
A FSH-Secreting Pituitary Macroadenoma Causing A Testosterone Deficiency Syndrome
title A FSH-Secreting Pituitary Macroadenoma Causing A Testosterone Deficiency Syndrome
title_full A FSH-Secreting Pituitary Macroadenoma Causing A Testosterone Deficiency Syndrome
title_fullStr A FSH-Secreting Pituitary Macroadenoma Causing A Testosterone Deficiency Syndrome
title_full_unstemmed A FSH-Secreting Pituitary Macroadenoma Causing A Testosterone Deficiency Syndrome
title_short A FSH-Secreting Pituitary Macroadenoma Causing A Testosterone Deficiency Syndrome
title_sort fsh-secreting pituitary macroadenoma causing a testosterone deficiency syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973166/
https://www.ncbi.nlm.nih.gov/pubmed/24696774
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