URI regulates tumorigenicity and chemotherapeutic resistance of multiple myeloma by modulating IL-6 transcription

Unconventional prefoldin RPB5 interactor (URI), which acts as an oncoprotein in solid tumors, is associated with RNA polymerase II subunit 5. However, its impact on multiple myeloma (MM) has not been determined. We demonstrate here that URI is overexpressed in MM compared with plasma cells derived f...

Descripción completa

Detalles Bibliográficos
Autores principales: Fan, J-L, Zhang, J, Dong, L-W, Fu, W-J, Du, J, Shi, H-G, Jiang, H, Ye, F, Xi, H, Zhang, C-Y, Hou, J, Wang, H-Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973192/
https://www.ncbi.nlm.nih.gov/pubmed/24625985
http://dx.doi.org/10.1038/cddis.2014.93

Ejemplares similares

Ejemplares similares