Depletion of pre-mRNA splicing factor Cdc5L inhibits mitotic progression and triggers mitotic catastrophe

Disturbing mitotic progression via targeted anti-mitotic therapy is an attractive strategy for cancer treatment. Therefore, the exploration and elucidation of molecular targets and pathways in mitosis are critical for the development of anti-mitotic drugs. Here, we show that cell division cycle 5-li...

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Detalles Bibliográficos
Autores principales: Mu, R, Wang, Y-B, Wu, M, Yang, Y, Song, W, Li, T, Zhang, W-N, Tan, B, Li, A-L, Wang, N, Xia, Q, Gong, W-L, Wang, C-G, Zhou, T, Guo, N, Sang, Z-H, Li, H-Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973201/
https://www.ncbi.nlm.nih.gov/pubmed/24675469
http://dx.doi.org/10.1038/cddis.2014.117

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