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Pivotal role of protein tyrosine phosphatase 1B (PTP1B) in the macrophage response to pro-inflammatory and anti-inflammatory challenge
Inhibition of protein tyrosine phosphatase 1B (PTP1B) has been suggested as an attractive target to improve insulin sensitivity in different cell types. In the present work, we have investigated the effect of PTP1B deficiency on the response of human and murine macrophages. Using in vitro and in viv...
Autores principales: | Través, P G, Pardo, V, Pimentel-Santillana, M, González-Rodríguez, Á, Mojena, M, Rico, D, Montenegro, Y, Calés, C, Martín-Sanz, P, Valverde, A M, Boscá, L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973223/ https://www.ncbi.nlm.nih.gov/pubmed/24625984 http://dx.doi.org/10.1038/cddis.2014.90 |
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