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Structure modulation of helix 69 from Escherichia coli 23S ribosomal RNA by pseudouridylations

Helix 69 (H69) is a 19-nt stem-loop region from the large subunit ribosomal RNA. Three pseudouridine (Ψ) modifications clustered in H69 are conserved across phylogeny and known to affect ribosome function. To explore the effects of Ψ on the conformations of Escherichia coli H69 in solution, nuclear...

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Detalles Bibliográficos
Autores principales:	Jiang, Jun, Aduri, Raviprasad, Chow, Christine S., SantaLucia, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973299/ https://www.ncbi.nlm.nih.gov/pubmed/24371282 http://dx.doi.org/10.1093/nar/gkt1329

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