The amino terminal extension of mammalian mitochondrial RNA polymerase ensures promoter specific transcription initiation

Mammalian mitochondrial transcription is executed by a single subunit mitochondrial RNA polymerase (Polrmt) and its two accessory factors, mitochondrial transcription factors A and B2 (Tfam and Tfb2m). Polrmt is structurally related to single-subunit phage RNA polymerases, but it also contains a uni...

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Detalles Bibliográficos
Autores principales: Posse, Viktor, Hoberg, Emily, Dierckx, Anke, Shahzad, Saba, Koolmeister, Camilla, Larsson, Nils-Göran, Wilhelmsson, L. Marcus, Hällberg, B. Martin, Gustafsson, Claes M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973307/
https://www.ncbi.nlm.nih.gov/pubmed/24445803
http://dx.doi.org/10.1093/nar/gkt1397

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