Structural insight into the specificity of the B3 DNA-binding domains provided by the co-crystal structure of the C-terminal fragment of BfiI restriction enzyme

The B3 DNA-binding domains (DBDs) of plant transcription factors (TF) and DBDs of EcoRII and BfiI restriction endonucleases (EcoRII-N and BfiI-C) share a common structural fold, classified as the DNA-binding pseudobarrel. The B3 DBDs in the plant TFs recognize a diverse set of target sequences. The...

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Detalles Bibliográficos
Autores principales: Golovenko, Dmitrij, Manakova, Elena, Zakrys, Linas, Zaremba, Mindaugas, Sasnauskas, Giedrius, Gražulis, Saulius, Siksnys, Virginijus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973309/
https://www.ncbi.nlm.nih.gov/pubmed/24423868
http://dx.doi.org/10.1093/nar/gkt1368

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