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Incorporation of thio-pseudoisocytosine into triplex-forming peptide nucleic acids for enhanced recognition of RNA duplexes

Peptide nucleic acids (PNAs) have been developed for applications in biotechnology and therapeutics. There is great potential in the development of chemically modified PNAs or other triplex-forming ligands that selectively bind to RNA duplexes, but not single-stranded regions, at near-physiological...

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Detalles Bibliográficos
Autores principales: Devi, Gitali, Yuan, Zhen, Lu, Yunpeng, Zhao, Yanli, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973316/
https://www.ncbi.nlm.nih.gov/pubmed/24423869
http://dx.doi.org/10.1093/nar/gkt1367