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Distinct tRNA recognition strategies used by a homologous family of editing domains prevent mistranslation

Errors in protein synthesis due to mispairing of amino acids with tRNAs jeopardize cell viability. Several checkpoints to prevent formation of Ala- and Cys-tRNA(Pro) have been described, including the Ala-specific editing domain (INS) of most bacterial prolyl-tRNA synthetases (ProRSs) and an autonom...

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Detalles Bibliográficos
Autores principales:	Das, Mom, Vargas-Rodriguez, Oscar, Goto, Yuki, Suga, Hiroaki, Musier-Forsyth, Karin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973320/ https://www.ncbi.nlm.nih.gov/pubmed/24371276 http://dx.doi.org/10.1093/nar/gkt1332

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