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AUF1 contributes to Cryptochrome1 mRNA degradation and rhythmic translation
In the present study, we investigated the 3′ untranslated region (UTR) of the mouse core clock gene cryptochrome 1 (Cry1) at the post-transcriptional level, particularly its translational regulation. Interestingly, the 3′UTR of Cry1 mRNA decreased its mRNA levels but increased protein amounts. The 3...
Autores principales: | Lee, Kyung-Ha, Kim, Sung-Hoon, Kim, Hyo-Jin, Kim, Wanil, Lee, Hwa-Rim, Jung, Youngseob, Choi, Jung-Hyun, Hong, Ka Young, Jang, Sung Key, Kim, Kyong-Tai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973335/ https://www.ncbi.nlm.nih.gov/pubmed/24423872 http://dx.doi.org/10.1093/nar/gkt1379 |
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