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Three-tiered role of the pioneer factor GATA2 in promoting androgen-dependent gene expression in prostate cancer

In prostate cancer, androgen receptor (AR) binding and androgen-responsive gene expression are defined by hormone-independent binding patterns of the pioneer factors FoxA1 and GATA2. Insufficient evidence of the mechanisms by which GATA2 contributes to this process precludes complete understanding o...

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Detalles Bibliográficos
Autores principales: Wu, Dayong, Sunkel, Benjamin, Chen, Zhong, Liu, Xiangtao, Ye, Zhenqing, Li, Qianjin, Grenade, Cassandra, Ke, Jingdong, Zhang, Chunpeng, Chen, Hongyan, Nephew, Kenneth P., Huang, Tim H.-M., Liu, Zhihua, Jin, Victor X., Wang, Qianben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973339/
https://www.ncbi.nlm.nih.gov/pubmed/24423874
http://dx.doi.org/10.1093/nar/gkt1382