The structure of metallo-DNA with consecutive thymine–Hg(II)–thymine base pairs explains positive entropy for the metallo base pair formation

We have determined the three-dimensional (3D) structure of DNA duplex that includes tandem Hg(II)-mediated T–T base pairs (thymine–Hg(II)–thymine, T–Hg(II)–T) with NMR spectroscopy in solution. This is the first 3D structure of metallo-DNA (covalently metallated DNA) composed exclusively of ‘NATURAL...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Hiroshi, Šebera, Jakub, Kondo, Jiro, Oda, Shuji, Komuro, Tomoyuki, Kawamura, Takuya, Dairaku, Takenori, Kondo, Yoshinori, Okamoto, Itaru, Ono, Akira, Burda, Jaroslav V., Kojima, Chojiro, Sychrovský, Vladimír, Tanaka, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973346/
https://www.ncbi.nlm.nih.gov/pubmed/24371287
http://dx.doi.org/10.1093/nar/gkt1344

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