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Genome metabolome integrated network analysis to uncover connections between genetic variants and complex traits: an application to obesity

Current studies of phenotype diversity by genome-wide association studies (GWAS) are mainly focused on identifying genetic variants that influence level changes of individual traits without considering additional alterations at the system-level. However, in addition to level alterations of single ph...

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Detalles Bibliográficos
Autores principales: Valcárcel, Beatriz, Ebbels, Timothy M. D., Kangas, Antti J., Soininen, Pasi, Elliot, Paul, Ala-Korpela, Mika, Järvelin, Marjo-Riitta, de Iorio, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973353/
https://www.ncbi.nlm.nih.gov/pubmed/24573330
http://dx.doi.org/10.1098/rsif.2013.0908