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Simultaneous reconstruction of evolutionary history and epidemiological dynamics from viral sequences with the birth–death SIR model
The evolution of RNA viruses, such as human immunodeficiency virus (HIV), hepatitis C virus and influenza virus, occurs so rapidly that the viruses' genomes contain information on past ecological dynamics. Hence, we develop a phylodynamic method that enables the joint estimation of epidemiologi...
Autores principales: | Kühnert, Denise, Stadler, Tanja, Vaughan, Timothy G., Drummond, Alexei J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973358/ https://www.ncbi.nlm.nih.gov/pubmed/24573331 http://dx.doi.org/10.1098/rsif.2013.1106 |
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