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Human cytomegalovirus suppresses Fas expression and function

Human cytomegalovirus (HCMV) is known to evade extrinsic pro-apoptotic pathways not only by downregulating cell surface expression of the death receptors TNFR1, TRAIL receptor 1 (TNFRSF10A) and TRAIL receptor 2 (TNFRSF10B), but also by impeding downstream signalling events. Fas (CD95/APO-1/TNFRSF6)...

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Detalles Bibliográficos
Autores principales: Seirafian, Sepehr, Prod’homme, Virginie, Sugrue, Daniel, Davies, James, Fielding, Ceri, Tomasec, Peter, Wilkinson, Gavin W. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973480/
https://www.ncbi.nlm.nih.gov/pubmed/24394698
http://dx.doi.org/10.1099/vir.0.058313-0