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Activation of Mu Opioid Receptors Sensitizes Transient Receptor Potential Vanilloid Type 1 (TRPV1) via β-Arrestin-2-Mediated Cross-Talk

The transient receptor potential family V1 channel (TRPV1) is activated by multiple stimuli, including capsaicin, acid, endovanilloids, and heat (>42C). Post-translational modifications to TRPV1 result in dynamic changes to the sensitivity of receptor activation. We have previously demonstrated t...

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Detalles Bibliográficos
Autores principales: Rowan, Matthew P., Bierbower, Sonya M., Eskander, Michael A., Szteyn, Kalina, Por, Elaine D., Gomez, Ruben, Veldhuis, Nicholas, Bunnett, Nigel W., Jeske, Nathaniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973553/
https://www.ncbi.nlm.nih.gov/pubmed/24695785
http://dx.doi.org/10.1371/journal.pone.0093688