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Activation of Mu Opioid Receptors Sensitizes Transient Receptor Potential Vanilloid Type 1 (TRPV1) via β-Arrestin-2-Mediated Cross-Talk
The transient receptor potential family V1 channel (TRPV1) is activated by multiple stimuli, including capsaicin, acid, endovanilloids, and heat (>42C). Post-translational modifications to TRPV1 result in dynamic changes to the sensitivity of receptor activation. We have previously demonstrated t...
Autores principales: | Rowan, Matthew P., Bierbower, Sonya M., Eskander, Michael A., Szteyn, Kalina, Por, Elaine D., Gomez, Ruben, Veldhuis, Nicholas, Bunnett, Nigel W., Jeske, Nathaniel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973553/ https://www.ncbi.nlm.nih.gov/pubmed/24695785 http://dx.doi.org/10.1371/journal.pone.0093688 |
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