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Apelin Increases Cardiac Contractility via Protein Kinase Cε- and Extracellular Signal-Regulated Kinase-Dependent Mechanisms

BACKGROUND: Apelin, the endogenous ligand for the G protein-coupled apelin receptor, is an important regulator of the cardiovascular homoeostasis. We previously demonstrated that apelin is one of the most potent endogenous stimulators of cardiac contractility; however, its underlying signaling mecha...

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Detalles Bibliográficos
Autores principales:	Perjés, Ábel, Skoumal, Réka, Tenhunen, Olli, Kónyi, Attila, Simon, Mihály, Horváth, Iván G., Kerkelä, Risto, Ruskoaho, Heikki, Szokodi, István
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973555/ https://www.ncbi.nlm.nih.gov/pubmed/24695532 http://dx.doi.org/10.1371/journal.pone.0093473

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