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TRAIL-R1 Is a Negative Regulator of Pro-Inflammatory Responses and Modulates Long-Term Sequelae Resulting from Chlamydia trachomatis Infections in Humans

The immune system eliminates Chlamydia trachomatis infection through inflammation. However, uncontrolled inflammation can enhance pathology. In mice, TNF-related apoptosis-inducing ligand receptor (TRAIL-R), known for its effects on apoptosis, also regulates inflammation. In humans, the four homolog...

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Detalles Bibliográficos
Autores principales: Al-Kuhlani, Mufadhal, Rothchild, James, Pal, Sukumar, de la Maza, Luis M., Ouburg, Sander, Morré, Servaas A., Dean, Deborah, Ojcius, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973638/
https://www.ncbi.nlm.nih.gov/pubmed/24695582
http://dx.doi.org/10.1371/journal.pone.0093939