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Finding Near-Optimal Groups of Epidemic Spreaders in a Complex Network

In this paper, we present algorithms to find near-optimal sets of epidemic spreaders in complex networks. We extend the notion of local-centrality, a centrality measure previously shown to correspond with a node's ability to spread an epidemic, to sets of nodes by introducing combinatorial loca...

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Detalles Bibliográficos
Autores principales: Moores, Geoffrey, Shakarian, Paulo, Macdonald, Brian, Howard, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973667/
https://www.ncbi.nlm.nih.gov/pubmed/24694693
http://dx.doi.org/10.1371/journal.pone.0090303
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author Moores, Geoffrey
Shakarian, Paulo
Macdonald, Brian
Howard, Nicholas
author_facet Moores, Geoffrey
Shakarian, Paulo
Macdonald, Brian
Howard, Nicholas
author_sort Moores, Geoffrey
collection PubMed
description In this paper, we present algorithms to find near-optimal sets of epidemic spreaders in complex networks. We extend the notion of local-centrality, a centrality measure previously shown to correspond with a node's ability to spread an epidemic, to sets of nodes by introducing combinatorial local centrality. Though we prove that finding a set of nodes that maximizes this new measure is NP-hard, good approximations are available. We show that a strictly greedy approach obtains the best approximation ratio unless P = NP and then formulate a modified version of this approach that leverages qualities of the network to achieve a faster runtime while maintaining this theoretical guarantee. We perform an experimental evaluation on samples from several different network structures which demonstrate that our algorithm maximizes combinatorial local centrality and consistently chooses the most effective set of nodes to spread infection under the SIR model, relative to selecting the top nodes using many common centrality measures. We also demonstrate that the optimized algorithm we develop scales effectively.
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spelling pubmed-39736672014-04-04 Finding Near-Optimal Groups of Epidemic Spreaders in a Complex Network Moores, Geoffrey Shakarian, Paulo Macdonald, Brian Howard, Nicholas PLoS One Research Article In this paper, we present algorithms to find near-optimal sets of epidemic spreaders in complex networks. We extend the notion of local-centrality, a centrality measure previously shown to correspond with a node's ability to spread an epidemic, to sets of nodes by introducing combinatorial local centrality. Though we prove that finding a set of nodes that maximizes this new measure is NP-hard, good approximations are available. We show that a strictly greedy approach obtains the best approximation ratio unless P = NP and then formulate a modified version of this approach that leverages qualities of the network to achieve a faster runtime while maintaining this theoretical guarantee. We perform an experimental evaluation on samples from several different network structures which demonstrate that our algorithm maximizes combinatorial local centrality and consistently chooses the most effective set of nodes to spread infection under the SIR model, relative to selecting the top nodes using many common centrality measures. We also demonstrate that the optimized algorithm we develop scales effectively. Public Library of Science 2014-04-02 /pmc/articles/PMC3973667/ /pubmed/24694693 http://dx.doi.org/10.1371/journal.pone.0090303 Text en https://creativecommons.org/publicdomain/zero/1.0/ This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.
spellingShingle Research Article
Moores, Geoffrey
Shakarian, Paulo
Macdonald, Brian
Howard, Nicholas
Finding Near-Optimal Groups of Epidemic Spreaders in a Complex Network
title Finding Near-Optimal Groups of Epidemic Spreaders in a Complex Network
title_full Finding Near-Optimal Groups of Epidemic Spreaders in a Complex Network
title_fullStr Finding Near-Optimal Groups of Epidemic Spreaders in a Complex Network
title_full_unstemmed Finding Near-Optimal Groups of Epidemic Spreaders in a Complex Network
title_short Finding Near-Optimal Groups of Epidemic Spreaders in a Complex Network
title_sort finding near-optimal groups of epidemic spreaders in a complex network
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973667/
https://www.ncbi.nlm.nih.gov/pubmed/24694693
http://dx.doi.org/10.1371/journal.pone.0090303
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