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Direct, Acute Effects of Klotho and FGF23 on Vascular Smooth Muscle and Endothelium

Chronic kidney disease (CKD) is regarded as a state of Klotho deficiency and FGF23 excess. In patients with CKD a strong association has been found between increased serum FGF23 and mortality risk, possibly via enhanced atherosclerosis, vascular stiffness, and vascular calcification. The aim of this...

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Detalles Bibliográficos
Autores principales:	Six, Isabelle, Okazaki, Hirokazu, Gross, Priscilla, Cagnard, Joanna, Boudot, Cédric, Maizel, Julien, Drueke, Tilman B., Massy, Ziad A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973676/ https://www.ncbi.nlm.nih.gov/pubmed/24695641 http://dx.doi.org/10.1371/journal.pone.0093423

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