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Krüppel Like Factor 4 Promoter Undergoes Active Demethylation during Monocyte/Macrophage Differentiation
The role of different lineage specific transcription factors in directing hematopoietic cell fate towards myeloid lineage is well established but the status of epigenetic modifications has not been defined during this important developmental process. We used non proliferating, PU.1 inducible myeloid...
Autores principales: | Karpurapu, Manjula, Ranjan, Ravi, Deng, Jing, Chung, Sangwoon, Lee, Yong Gyu, Xiao, Lei, Nirujogi, Teja Srinivas, Jacobson, Jeffrey R., Park, Gye Young, Christman, John W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973678/ https://www.ncbi.nlm.nih.gov/pubmed/24695324 http://dx.doi.org/10.1371/journal.pone.0093362 |
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