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Epidermal or Dermal Specific Knockout of PHD-2 Enhances Wound Healing and Minimizes Ischemic Injury

INTRODUCTION: Hypoxia-inducible factor (HIF)-1α, part of the heterodimeric transcription factor that mediates the cellular response to hypoxia, is critical for the expression of multiple angiogenic growth factors, cell motility, and the recruitment of endothelial progenitor cells. Inhibition of the...

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Detalles Bibliográficos
Autores principales:	Zimmermann, Andrew S., Morrison, Shane D., Hu, Michael S., Li, Shuli, Nauta, Allison, Sorkin, Michael, Meyer, Nathaniel P., Walmsley, Graham G., Maan, Zeshaan N., Chan, Denise A., Gurtner, Geoffrey C., Giaccia, Amato J., Longaker, Michael T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973687/ https://www.ncbi.nlm.nih.gov/pubmed/24695462 http://dx.doi.org/10.1371/journal.pone.0093373

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