Cargando…

Polymorphisms in the glutathione pathway modulate cystic fibrosis severity: a cross-sectional study

BACKGROUND: Cystic fibrosis (CF) clinically manifests with various levels of severity, which are thought to be modulated by mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR), modifier genes, and the environment. This study verified whether polymorphisms in modifier gen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marson, Fernando Augusto de Lima, Bertuzzo, Carmen Silvia, Ribeiro, Antonio Fernando, Ribeiro, Jose Dirceu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973994/ https://www.ncbi.nlm.nih.gov/pubmed/24593045 http://dx.doi.org/10.1186/1471-2350-15-27

Ejemplares similares

Genetic interaction of GSH metabolic pathway genes in cystic fibrosis
por: Marson, Fernando Augusto de Lima, et al.
Publicado: (2013)

Cystic fibrosis transmembrane conductance regulator mutations at a referral center for cystic fibrosis
por: Coutinho, Cyntia Arivabeni de Araújo Correia, et al.
Publicado: (2013)

Polymorphisms in ADRB2 gene can modulate the response to bronchodilators and the severity of cystic fibrosis
por: Marson, Fernando A L, et al.
Publicado: (2012)

Screening for F508del as a first step in the molecular diagnosis of cystic fibrosis,
por: Marson, Fernando Augusto de Lima, et al.
Publicado: (2013)

The ACE gene D/I polymorphism as a modulator of severity of cystic fibrosis
por: Marson, Fernando A L, et al.
Publicado: (2012)

Nasal Potential Difference in Cystic Fibrosis considering Severe CFTR Mutations
por: Ng, Ronny Tah Yen, et al.
Publicado: (2015)

Association between the IVS4G > T mutation in the TCF7L2 gene and susceptibility to diabetes in cystic fibrosis patients
por: Furgeri, Daniela Tenório, et al.
Publicado: (2012)

Personalized or Precision Medicine? The Example of Cystic Fibrosis
por: Marson, Fernando A. L., et al.
Publicado: (2017)

Asthma: Gln27Glu and Arg16Gly polymorphisms of the beta2-adrenergic receptor gene as risk factors
por: de Paiva, Ana Carolina Zimiani, et al.
Publicado: (2014)

SLC23A2-05 (rs4987219) and KRAS-LCS6 (rs61764370) polymorphisms in patients with squamous cell carcinoma of the head and neck
por: SANTIAGO, MARÍLIA BUENO, et al.
Publicado: (2014)

Novel, rare and common pathogenic variants in the CFTR gene screened by high-throughput sequencing technology and predicted by in silico tools
por: Pereira, Stéphanie Villa-Nova, et al.
Publicado: (2019)

Saliva as a potential tool for cystic fibrosis diagnosis
por: Gonçalves, Aline Cristina, et al.
Publicado: (2013)

Demographic, clinical, and laboratory parameters of cystic fibrosis during the last two decades: a comparative analysis
por: Marson, Fernando Augusto de Lima, et al.
Publicado: (2015)

Can continuous glucose monitoring predict cystic fibrosis-related diabetes and worse clinical outcome?
por: Zorron, Mariana, et al.
Publicado: (2022)

Lung ultrasound assessment of response to antibiotic therapy in cystic fibrosis exacerbations: a study of two cases
por: Peixoto, Andressa Oliveira, et al.
Publicado: (2019)

Factors impacting the growth and nutritional status of cystic fibrosis patients younger than 10 years of age who did not undergo neonatal screening
por: Hortencio, Taís Daiene Russo, et al.
Publicado: (2015)

Glutathione S-transferase mu 1 (GSTM1) and theta 1 (GSTT1) genetic polymorphisms and atopic asthma in children from Southeastern Brazil
por: Lima, Carmen Silvia Passos, et al.
Publicado: (2010)

Volumetric capnography versus spirometry for the evaluation of pulmonary function in cystic fibrosis and allergic asthma()()
por: Almeida-Junior, Armando, et al.
Publicado: (2018)

Sweat test and cystic fibrosis: overview of test performance at public and private centers in the state of São Paulo, Brazil
por: Servidoni, Maria Fátima, et al.
Publicado: (2017)

Cost of precision medicine at a referral center for cystic fibrosis
por: Marson, Fernando Augusto Lima
Publicado: (2020)

Association of growth and nutritional parameters with pulmonary function in cystic fibrosis: a literature review
por: Mauch, Renan Marrichi, et al.
Publicado: (2016)

Evaluation of continuous constant current and continuous pulsed current in sweat induction for cystic fibrosis diagnosis
por: Gomez, Carla Cristina Souza, et al.
Publicado: (2018)

Thymidylate synthase gene (TYMS) polymorphisms in sporadic and hereditary breast cancer
por: Junior, José da Silva Nogueira, et al.
Publicado: (2012)

Ventilatory abnormalities in patients with cystic fibrosis undergoing the submaximal treadmill exercise test
por: Parazzi, Paloma Lopes Francisco, et al.
Publicado: (2015)

Challenges in Diagnosing Primary Ciliary Dyskinesia in a Brazilian Tertiary Hospital
por: Toro, Mariana Dalbo Contrera, et al.
Publicado: (2022)

Quality of sweat test (ST) based on the proportion of sweat sodium (Na) and sweat chloride (Cl) as diagnostic parameter of cystic fibrosis: are we on the right way?
por: Faria, Alethéa Guimarães, et al.
Publicado: (2016)

Erratum to: Quality of sweat test (ST) based on the proportion of sweat sodium (Na) and sweat chloride (Cl) as diagnostic parameter of cystic fibrosis: are we on the right way?
por: Faria, Alethéa Guimarães, et al.
Publicado: (2017)

Combined multi-channel intraluminal impedance measurement and pHmetry in the detection of gastroesophageal reflux disease in children with cystic fibrosis
por: Gonçalves, Emília da Silva, et al.
Publicado: (2022)

Cystic Fibrosis: A Descriptive Analysis of Deaths in a Two-Decade Period in Brazil According to Age, Race, and Sex
por: de Azevedo, Luan Victor Frota, et al.
Publicado: (2023)

Measurements of CFTR-Mediated Cl(−) Secretion in Human Rectal Biopsies Constitute a Robust Biomarker for Cystic Fibrosis Diagnosis and Prognosis
por: Sousa, Marisa, et al.
Publicado: (2012)

Epidemiological Profile of Hospitalized Patients with Cystic Fibrosis in Brazil Due to Severe Acute Respiratory Infection during the COVID-19 Pandemic and a Systematic Review of Worldwide COVID-19 in Those with Cystic Fibrosis
por: Marques, Leonardo Souza, et al.
Publicado: (2023)

Severe pulmonary disease in an adult primary ciliary dyskinesia population in Brazil
por: Olm, Mary Anne Kowal, et al.
Publicado: (2019)

Insulin therapy in patients with cystic fibrosis in the pre-diabetes stage: a systematic review
por: Pu, Mariana Zorrón Mei Hsia, et al.
Publicado: (2016)

Epidemiological aspects of and risk factors for wheezing in the first year of life
por: Fogaça, Hamilton Rosendo, et al.
Publicado: (2014)

Skin Biomarkers for Cystic Fibrosis: A Potential Non-Invasive Approach for Patient Screening
por: Esteves, Cibele Zanardi, et al.
Publicado: (2018)

Assessment of IgG antibodies to Pseudomonas aeruginosa in patients with cystic fibrosis by an enzyme-linked immunosorbent assay (ELISA)
por: Mauch, Renan Marrichi, et al.
Publicado: (2014)

Thirty Years of Sweat Chloride Testing at One Referral Center
por: Faria, Alethéa Guimarães, et al.
Publicado: (2017)

Lung function in obese children and adolescents without respiratory disease: a systematic review
por: Ferreira, Mariana Simões, et al.
Publicado: (2020)

Cross-sectional evaluation of the saccharin transit time test for primary ciliary dyskinesia: did we discard this tool too soon?
por: Toro, Mariana Dalbo Contrera, et al.
Publicado: (2023)

Correlation between acoustic rhinometry, computed rhinomanometry and cone-beam computed tomography in mouth breathers with transverse maxillary deficiency()
por: Sakai, Raquel Harumi Uejima Satto, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_tmv6jr8bccp15985n67s5nrban