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Femur shaft fracture at a young age and the risk of subsequent severe injuries during childhood: a cohort study
BACKGROUND: A child who suffers a fracture or a soft-tissue injury at a young age faces an increased risk of subsequent injuries during childhood. This risk could be related to personal and family characteristics or to lower-than-average bone-mineral density. The purpose of this nationwide cohort st...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974004/ https://www.ncbi.nlm.nih.gov/pubmed/24589362 http://dx.doi.org/10.1186/1471-2431-14-62 |
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author | von Heideken, Johan Svensson, Tobias Iversen, Maura Ekbom, Anders Janarv, Per-Mats |
author_facet | von Heideken, Johan Svensson, Tobias Iversen, Maura Ekbom, Anders Janarv, Per-Mats |
author_sort | von Heideken, Johan |
collection | PubMed |
description | BACKGROUND: A child who suffers a fracture or a soft-tissue injury at a young age faces an increased risk of subsequent injuries during childhood. This risk could be related to personal and family characteristics or to lower-than-average bone-mineral density. The purpose of this nationwide cohort study was to estimate the association between a femur shaft fracture at a young age and the subsequent risk of hospitalization for injuries during childhood. METHODS: We compared the subsequent risk of hospitalization for injuries during childhood among 1,404 children (exposed) who were one to three years of age when they suffered a femur shaft fracture with the risk among 13,814 randomly selected, gender- and age-matched femur fracture–free children (unexposed). Hazard ratios (HRs) and 95% confidence intervals (CIs) for severe injuries defined as fractures or soft-tissue injuries requiring hospital admission were estimated in a Cox proportional hazards model. RESULTS: Exposed children exhibited no significantly increased risk of upper-extremity fractures or soft-tissue injuries during childhood, regardless of sex and follow-up time. Boys exhibited a 162% increased risk of suffering a lower leg fracture requiring hospital admission (HR?=?2.62, 95% CI: 1.45–4.71), but the refracture risk was not significant for girls 2.02 (0.58–6.97). CONCLUSIONS: We found an increased risk for subsequent fractures in the lower leg that requires inpatient care during childhood for boys, but not for girls, who were one to three years of age when they first suffered a femur shaft fracture. This increased fracture risk is probably not simply the result of greater risk-taking among boys. The explanation might relate to factors affecting the bone quality of the lower leg. |
format | Online Article Text |
id | pubmed-3974004 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-39740042014-04-04 Femur shaft fracture at a young age and the risk of subsequent severe injuries during childhood: a cohort study von Heideken, Johan Svensson, Tobias Iversen, Maura Ekbom, Anders Janarv, Per-Mats BMC Pediatr Research Article BACKGROUND: A child who suffers a fracture or a soft-tissue injury at a young age faces an increased risk of subsequent injuries during childhood. This risk could be related to personal and family characteristics or to lower-than-average bone-mineral density. The purpose of this nationwide cohort study was to estimate the association between a femur shaft fracture at a young age and the subsequent risk of hospitalization for injuries during childhood. METHODS: We compared the subsequent risk of hospitalization for injuries during childhood among 1,404 children (exposed) who were one to three years of age when they suffered a femur shaft fracture with the risk among 13,814 randomly selected, gender- and age-matched femur fracture–free children (unexposed). Hazard ratios (HRs) and 95% confidence intervals (CIs) for severe injuries defined as fractures or soft-tissue injuries requiring hospital admission were estimated in a Cox proportional hazards model. RESULTS: Exposed children exhibited no significantly increased risk of upper-extremity fractures or soft-tissue injuries during childhood, regardless of sex and follow-up time. Boys exhibited a 162% increased risk of suffering a lower leg fracture requiring hospital admission (HR?=?2.62, 95% CI: 1.45–4.71), but the refracture risk was not significant for girls 2.02 (0.58–6.97). CONCLUSIONS: We found an increased risk for subsequent fractures in the lower leg that requires inpatient care during childhood for boys, but not for girls, who were one to three years of age when they first suffered a femur shaft fracture. This increased fracture risk is probably not simply the result of greater risk-taking among boys. The explanation might relate to factors affecting the bone quality of the lower leg. BioMed Central 2014-03-03 /pmc/articles/PMC3974004/ /pubmed/24589362 http://dx.doi.org/10.1186/1471-2431-14-62 Text en Copyright © 2014 von Heideken et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article von Heideken, Johan Svensson, Tobias Iversen, Maura Ekbom, Anders Janarv, Per-Mats Femur shaft fracture at a young age and the risk of subsequent severe injuries during childhood: a cohort study |
title | Femur shaft fracture at a young age and the risk of subsequent severe injuries during childhood: a cohort study |
title_full | Femur shaft fracture at a young age and the risk of subsequent severe injuries during childhood: a cohort study |
title_fullStr | Femur shaft fracture at a young age and the risk of subsequent severe injuries during childhood: a cohort study |
title_full_unstemmed | Femur shaft fracture at a young age and the risk of subsequent severe injuries during childhood: a cohort study |
title_short | Femur shaft fracture at a young age and the risk of subsequent severe injuries during childhood: a cohort study |
title_sort | femur shaft fracture at a young age and the risk of subsequent severe injuries during childhood: a cohort study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974004/ https://www.ncbi.nlm.nih.gov/pubmed/24589362 http://dx.doi.org/10.1186/1471-2431-14-62 |
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