Increased IR-A/IR-B ratio in non-small cell lung cancers associates with lower epithelial-mesenchymal transition signature and longer survival in squamous cell lung carcinoma

BACKGROUND: To evaluate the insulin receptor isoform mRNA expression status in non-small cell lung cancer (NSCLC) patients. METHODS: RNA-seq data from 614 NSCLC [355 adenocarcinomas (LUAD) and 259 squamous cell carcinomas (LUSC)] and 92 normal lung specimens were obtained from The Cancer Genome Atla...

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Detalles Bibliográficos
Autores principales: Jiang, Liyan, Zhu, Wei, Streicher, Katie, Morehouse, Chris, Brohawn, Philip, Ge, Xiaoxiao, Dong, Zhengwei, Yin, Xiaolu, Zhu, Guanshan, Gu, Yi, Ranade, Koustubh, Higgs, Brandon W, Yao, Yihong, Huang, Jiaqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974050/
https://www.ncbi.nlm.nih.gov/pubmed/24571613
http://dx.doi.org/10.1186/1471-2407-14-131

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