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The Vibrio cholerae diguanylate cyclase VCA0965 has an AGDEF active site and synthesizes cyclic di-GMP

BACKGROUND: Diguanylate cyclases (DGCs) regulate biofilm formation and motility in bacteria by synthesizing the second messenger cyclic di-GMP (c-di-GMP) in response to environmental stimuli. DGC enzymatic activity is believed to be dependent on the presence of a GG(D/E)EF active site motif, however...

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Detalles Bibliográficos
Autores principales:	Hunter, Jessica L, Severin, Geoffrey B, Koestler, Benjamin J, Waters, Christopher M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974145/ https://www.ncbi.nlm.nih.gov/pubmed/24490592 http://dx.doi.org/10.1186/1471-2180-14-22

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