Management of plastic bronchitis with nebulized tissue plasminogen activator: another brick in the wall

Plastic bronchitis is a rare complication of a variety of respiratory diseases and congenital heart disease surgery, particularly Fontan procedure. Bronchial casts with rubber-like consistency develop acutely and may cause severe life-threatening respiratory distress. The management of plastic bronc...

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Autores principales: Colaneri, Massimo, Quarti, Andrea, Pozzi, Marco, Gasparini, Stefano, Carloni, Ines, de Benedictis, Fernando Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974171/
https://www.ncbi.nlm.nih.gov/pubmed/24524376
http://dx.doi.org/10.1186/1824-7288-40-18
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author Colaneri, Massimo
Quarti, Andrea
Pozzi, Marco
Gasparini, Stefano
Carloni, Ines
de Benedictis, Fernando Maria
author_facet Colaneri, Massimo
Quarti, Andrea
Pozzi, Marco
Gasparini, Stefano
Carloni, Ines
de Benedictis, Fernando Maria
author_sort Colaneri, Massimo
collection PubMed
description Plastic bronchitis is a rare complication of a variety of respiratory diseases and congenital heart disease surgery, particularly Fontan procedure. Bronchial casts with rubber-like consistency develop acutely and may cause severe life-threatening respiratory distress. The management of plastic bronchitis is yet not well defined. Early intermittent, self-administered nebulization of tissue plasminogen activator was found to be effective in preventing deterioration of acute respiratory symptoms in a patient with primary ciliary dyskinesia and recurrent cast formation. Further investigation into new therapeutic strategies for this devastating disease is advocated.
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spelling pubmed-39741712014-04-04 Management of plastic bronchitis with nebulized tissue plasminogen activator: another brick in the wall Colaneri, Massimo Quarti, Andrea Pozzi, Marco Gasparini, Stefano Carloni, Ines de Benedictis, Fernando Maria Ital J Pediatr Case Report Plastic bronchitis is a rare complication of a variety of respiratory diseases and congenital heart disease surgery, particularly Fontan procedure. Bronchial casts with rubber-like consistency develop acutely and may cause severe life-threatening respiratory distress. The management of plastic bronchitis is yet not well defined. Early intermittent, self-administered nebulization of tissue plasminogen activator was found to be effective in preventing deterioration of acute respiratory symptoms in a patient with primary ciliary dyskinesia and recurrent cast formation. Further investigation into new therapeutic strategies for this devastating disease is advocated. BioMed Central 2014-02-13 /pmc/articles/PMC3974171/ /pubmed/24524376 http://dx.doi.org/10.1186/1824-7288-40-18 Text en Copyright © 2014 Colaneri et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Colaneri, Massimo
Quarti, Andrea
Pozzi, Marco
Gasparini, Stefano
Carloni, Ines
de Benedictis, Fernando Maria
Management of plastic bronchitis with nebulized tissue plasminogen activator: another brick in the wall
title Management of plastic bronchitis with nebulized tissue plasminogen activator: another brick in the wall
title_full Management of plastic bronchitis with nebulized tissue plasminogen activator: another brick in the wall
title_fullStr Management of plastic bronchitis with nebulized tissue plasminogen activator: another brick in the wall
title_full_unstemmed Management of plastic bronchitis with nebulized tissue plasminogen activator: another brick in the wall
title_short Management of plastic bronchitis with nebulized tissue plasminogen activator: another brick in the wall
title_sort management of plastic bronchitis with nebulized tissue plasminogen activator: another brick in the wall
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974171/
https://www.ncbi.nlm.nih.gov/pubmed/24524376
http://dx.doi.org/10.1186/1824-7288-40-18
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