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Structure of the proton-gated urea channel from the gastric pathogen Helicobacter pylori
Half the world's population is chronically infected with Helicobacter pylori(1), causing gastritis, ulcers and increased incidence of gastric adenocarcinoma(2). Its proton-gated inner-membrane urea channel, HpUreI, is essential for survival in the acidic environment of the stomach(3). The chann...
Autores principales: | Strugatsky, David, McNulty, Reginald, Munson, Keith, Chen, Chiung-Kuang, Soltis, S. Michael, Sachs, George, Luecke, Hartmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974264/ https://www.ncbi.nlm.nih.gov/pubmed/23222544 http://dx.doi.org/10.1038/nature11684 |
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