The central molecular clock is robust in the face of behavioural arrhythmia in a Drosophila model of Alzheimer’s disease

Circadian behavioural deficits, including sleep irregularity and restlessness in the evening, are a distressing early feature of Alzheimer’s disease (AD). We have investigated these phenomena by studying the circadian behaviour of transgenic Drosophila expressing the amyloid beta peptide (Aβ). We fi...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Ko-Fan, Possidente, Bernard, Lomas, David A., Crowther, Damian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974455/
https://www.ncbi.nlm.nih.gov/pubmed/24574361
http://dx.doi.org/10.1242/dmm.014134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974455/
https://www.ncbi.nlm.nih.gov/pubmed/24574361
http://dx.doi.org/10.1242/dmm.014134

Ejemplares similares