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The central molecular clock is robust in the face of behavioural arrhythmia in a Drosophila model of Alzheimer’s disease
Circadian behavioural deficits, including sleep irregularity and restlessness in the evening, are a distressing early feature of Alzheimer’s disease (AD). We have investigated these phenomena by studying the circadian behaviour of transgenic Drosophila expressing the amyloid beta peptide (Aβ). We fi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Limited
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974455/ https://www.ncbi.nlm.nih.gov/pubmed/24574361 http://dx.doi.org/10.1242/dmm.014134 |