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Recognition of Watson-Crick base pairs: constraints and limits due to geometric selection and tautomerism
The natural bases of nucleic acids have a strong preference for one tautomer form, guaranteeing fidelity in their hydrogen bonding potential. However, base pairs observed in recent crystal structures of polymerases and ribosomes are best explained by an alternative base tautomer, leading to the form...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Faculty of 1000 Ltd
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974571/ https://www.ncbi.nlm.nih.gov/pubmed/24765524 http://dx.doi.org/10.12703/P6-19 |