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Targeted Delivery of Ubiquitin-Conjugated BH3 Peptide-Based Mcl-1 Inhibitors into Cancer Cells
[Image: see text] BH3 peptides are key mediators of apoptosis and have served as the lead structures for the development of anticancer therapeutics. Previously, we reported the application of a simple cysteine-based side chain cross-linking chemistry to NoxaBH3 peptides that led to the generation of...
Autores principales: | Muppidi, Avinash, Doi, Kenichiro, Edwardraja, Selvakumar, Pulavarti, Surya V. S. R. K., Szyperski, Thomas, Wang, Hong-Gang, Lin, Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974624/ https://www.ncbi.nlm.nih.gov/pubmed/24410055 http://dx.doi.org/10.1021/bc4005574 |
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