A LINE-1 Insertion in DLX6 Is Responsible for Cleft Palate and Mandibular Abnormalities in a Canine Model of Pierre Robin Sequence

Cleft palate (CP) is one of the most commonly occurring craniofacial birth defects in humans. In order to study cleft palate in a naturally occurring model system, we utilized the Nova Scotia Duck Tolling Retriever (NSDTR) dog breed. Micro-computed tomography analysis of CP NSDTR craniofacial struct...

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Detalles Bibliográficos
Autores principales: Wolf, Zena T., Leslie, Elizabeth J., Arzi, Boaz, Jayashankar, Kartika, Karmi, Nili, Jia, Zhonglin, Rowland, Douglas J., Young, Amy, Safra, Noa, Sliskovic, Saundra, Murray, Jeffrey C., Wade, Claire M., Bannasch, Danika L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974639/
https://www.ncbi.nlm.nih.gov/pubmed/24699068
http://dx.doi.org/10.1371/journal.pgen.1004257

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